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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleBrain

Automated CT Segmentation and Analysis for Acute Middle Cerebral Artery Stroke

Joseph A. Maldjian, Julio Chalela, Scott E. Kasner, David Liebeskind and John A. Detre
American Journal of Neuroradiology June 2001, 22 (6) 1050-1055;
Joseph A. Maldjian
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Julio Chalela
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Scott E. Kasner
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David Liebeskind
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John A. Detre
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    fig 1.

    Large left MCA stroke (patient case 1).

    A, Raw CT scan shows left MCA infarct predominantly involving the insula, with marginal involvement of the lentiform nucleus (right of image is left of patient).

    B, CT scan after automated scalp stripping and normalization to Talairach atlas (right of image is right of patient).

    C, Automated segmentation color coded onto normalized CT scan shows excellent registration of lentiform nucleus (red) and insular cortex (yellow). Internal capsule is displayed in green.

    D, Histogram plot for lentiform nucleus shows mild leftward shift for the left lentiform nucleus (dotted line, P < .0196 using a Wilcoxon statistic corrected for spatial autocorrelation).

    E, Histogram plot for insula shows a large leftward shift (P < 1 × 10−9).

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    fig 2.

    Subtle right MCA stroke (patient case 5).

    A, Raw CT scan shows subtle right MCA territory infarct (right of image is left of patient) involving the insula and posterior putamen.

    B, Posterior putamen and insula are highlighted.

    C, CT scan after automated scalp stripping and normalization to Talairach atlas (right of image is right of patient).

    D, Automated segmentation color coded onto normalized CT scan (as in fig 1) shows excellent registration of basal ganglia structures and insular cortex.

    E, Histogram plot for insula shows leftward shift for the right insula (solid line, P < 1 × 10−9).

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    TABLE 1:

    Control group histogram P values

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    TABLE 2:

    Patient histogram P values and CT interpretations

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    TABLE 3:

    Automated CT analysis summary for the patient group

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American Journal of Neuroradiology: 22 (6)
American Journal of Neuroradiology
Vol. 22, Issue 6
1 Jun 2001
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Cite this article
Joseph A. Maldjian, Julio Chalela, Scott E. Kasner, David Liebeskind, John A. Detre
Automated CT Segmentation and Analysis for Acute Middle Cerebral Artery Stroke
American Journal of Neuroradiology Jun 2001, 22 (6) 1050-1055;

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Automated CT Segmentation and Analysis for Acute Middle Cerebral Artery Stroke
Joseph A. Maldjian, Julio Chalela, Scott E. Kasner, David Liebeskind, John A. Detre
American Journal of Neuroradiology Jun 2001, 22 (6) 1050-1055;
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