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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleSpine Imaging and Spine Image-Guided Interventions

CT-guided Biopsy of Focal Lesions in Patients with Multiple Myeloma May Reveal New and More Aggressive Cytogenetic Abnormalities

Ramesh Avva, Rudy L. Vanhemert, Bart Barlogie, Nikhil Munshi and Edgardo J. Angtuaco
American Journal of Neuroradiology April 2001, 22 (4) 781-785;
Ramesh Avva
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Rudy L. Vanhemert
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Bart Barlogie
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Nikhil Munshi
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Edgardo J. Angtuaco
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    fig 1.

    Sacral plasmacytoma in a patient in the TT II trial. A, Coronal STIR T1-weighted image shows a large hyperintense plasmacytoma in the right sacral ala. B, CT-guided FNA of a large lytic lesion shows cytogenetic abnormalities, including chromosome 13 deletion

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    fig 2.

    T6 plasmacytoma of the posterior elements in a patient in the DTPACE trial. A, Sagittal STIR T1-weighted image shows a large hyperintense lesion involving the spinous process and right lamina. B, CT scan shows only a small lytic component, for which biopsy revealed chromosome 13 deletion.

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    TABLE 1:

    Biopsy sites

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    TABLE 2:

    TT II trial: cytogenetic results from CT-guided fine-needle aspiration biopsy and random marrow sampling

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    TABLE 3:

    DTPACE trial: cytogenetic results from CT-guided fine-needle aspiration biopsy and random marrow sampling

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American Journal of Neuroradiology
Vol. 22, Issue 4
1 Apr 2001
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Cite this article
Ramesh Avva, Rudy L. Vanhemert, Bart Barlogie, Nikhil Munshi, Edgardo J. Angtuaco
CT-guided Biopsy of Focal Lesions in Patients with Multiple Myeloma May Reveal New and More Aggressive Cytogenetic Abnormalities
American Journal of Neuroradiology Apr 2001, 22 (4) 781-785;

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CT-guided Biopsy of Focal Lesions in Patients with Multiple Myeloma May Reveal New and More Aggressive Cytogenetic Abnormalities
Ramesh Avva, Rudy L. Vanhemert, Bart Barlogie, Nikhil Munshi, Edgardo J. Angtuaco
American Journal of Neuroradiology Apr 2001, 22 (4) 781-785;
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  • Clonal competition with alternating dominance in multiple myeloma
  • Imaging of Multiple Myeloma and Related Plasma Cell Dyscrasias
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More in this TOC Section

  • Dynamic CT Myelography: Patient Positioning
  • Evaluation of SIH MR Scoring Systems in Normals
  • Characteristics of SIH Type I Culprit Lesions
Show more SPINE IMAGING AND SPINE IMAGE-GUIDED INTERVENTIONS

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