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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleBRAIN

MR Imaging Features of Clear-Cell Meningioma with Diffuse Leptomeningeal Seeding

Whal Lee, Kee-Hyun Chang, Gheeyoung Choe, Je G. Chi, Chun-Kee Chung, Il Han Kim, Moon Hee Han, Sun-Won Park, Sang June Shin and Young Hwan Koh
American Journal of Neuroradiology January 2000, 21 (1) 130-132;
Whal Lee
aFrom the Department of Radiology, Seoul National University College of Medicine (W.L., K.-H.C., M.H.H., S.-W.P., S.J.S., Y.H.K.); Neuroscience Research Institute, SNUMRC (K.-H.C., M.H.H.); Departments of Pathology (G.C., J.G.C.), Neurosurgery (C.-K.C.), and Therapeutic Radiology (I.H.K.), Seoul National University College of Medicine, Seoul, Korea.
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Kee-Hyun Chang
aFrom the Department of Radiology, Seoul National University College of Medicine (W.L., K.-H.C., M.H.H., S.-W.P., S.J.S., Y.H.K.); Neuroscience Research Institute, SNUMRC (K.-H.C., M.H.H.); Departments of Pathology (G.C., J.G.C.), Neurosurgery (C.-K.C.), and Therapeutic Radiology (I.H.K.), Seoul National University College of Medicine, Seoul, Korea.
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Gheeyoung Choe
aFrom the Department of Radiology, Seoul National University College of Medicine (W.L., K.-H.C., M.H.H., S.-W.P., S.J.S., Y.H.K.); Neuroscience Research Institute, SNUMRC (K.-H.C., M.H.H.); Departments of Pathology (G.C., J.G.C.), Neurosurgery (C.-K.C.), and Therapeutic Radiology (I.H.K.), Seoul National University College of Medicine, Seoul, Korea.
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Je G. Chi
aFrom the Department of Radiology, Seoul National University College of Medicine (W.L., K.-H.C., M.H.H., S.-W.P., S.J.S., Y.H.K.); Neuroscience Research Institute, SNUMRC (K.-H.C., M.H.H.); Departments of Pathology (G.C., J.G.C.), Neurosurgery (C.-K.C.), and Therapeutic Radiology (I.H.K.), Seoul National University College of Medicine, Seoul, Korea.
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Chun-Kee Chung
aFrom the Department of Radiology, Seoul National University College of Medicine (W.L., K.-H.C., M.H.H., S.-W.P., S.J.S., Y.H.K.); Neuroscience Research Institute, SNUMRC (K.-H.C., M.H.H.); Departments of Pathology (G.C., J.G.C.), Neurosurgery (C.-K.C.), and Therapeutic Radiology (I.H.K.), Seoul National University College of Medicine, Seoul, Korea.
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Il Han Kim
aFrom the Department of Radiology, Seoul National University College of Medicine (W.L., K.-H.C., M.H.H., S.-W.P., S.J.S., Y.H.K.); Neuroscience Research Institute, SNUMRC (K.-H.C., M.H.H.); Departments of Pathology (G.C., J.G.C.), Neurosurgery (C.-K.C.), and Therapeutic Radiology (I.H.K.), Seoul National University College of Medicine, Seoul, Korea.
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Moon Hee Han
aFrom the Department of Radiology, Seoul National University College of Medicine (W.L., K.-H.C., M.H.H., S.-W.P., S.J.S., Y.H.K.); Neuroscience Research Institute, SNUMRC (K.-H.C., M.H.H.); Departments of Pathology (G.C., J.G.C.), Neurosurgery (C.-K.C.), and Therapeutic Radiology (I.H.K.), Seoul National University College of Medicine, Seoul, Korea.
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Sun-Won Park
aFrom the Department of Radiology, Seoul National University College of Medicine (W.L., K.-H.C., M.H.H., S.-W.P., S.J.S., Y.H.K.); Neuroscience Research Institute, SNUMRC (K.-H.C., M.H.H.); Departments of Pathology (G.C., J.G.C.), Neurosurgery (C.-K.C.), and Therapeutic Radiology (I.H.K.), Seoul National University College of Medicine, Seoul, Korea.
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Sang June Shin
aFrom the Department of Radiology, Seoul National University College of Medicine (W.L., K.-H.C., M.H.H., S.-W.P., S.J.S., Y.H.K.); Neuroscience Research Institute, SNUMRC (K.-H.C., M.H.H.); Departments of Pathology (G.C., J.G.C.), Neurosurgery (C.-K.C.), and Therapeutic Radiology (I.H.K.), Seoul National University College of Medicine, Seoul, Korea.
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Young Hwan Koh
aFrom the Department of Radiology, Seoul National University College of Medicine (W.L., K.-H.C., M.H.H., S.-W.P., S.J.S., Y.H.K.); Neuroscience Research Institute, SNUMRC (K.-H.C., M.H.H.); Departments of Pathology (G.C., J.G.C.), Neurosurgery (C.-K.C.), and Therapeutic Radiology (I.H.K.), Seoul National University College of Medicine, Seoul, Korea.
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    fig 1.

     MR imaging findings of clear-cell meningioma with diffuse leptomeningeal seeding in 17-year-old man.

    A, Initial contrast-enhanced T1-weighted axial MR image shows 1 × 3-cm, strongly enhancing mass at left parietal convexity (arrow) associated with localized leptomeningeal enhancement in ipsilateral sylvian fissure (small arrows). Mild hydrocephalus is noted also. Mass was isointense on T1-weighted image and slightly hyperintense on T2-weighted image (not shown).

    B, Photomicrograph of cerebral tumor. Tumor is composed of back-to-back monotonous round cells with clear cytoplasm and fine nuclear chromatin. (hematoxylin & eosin stain, × 200).

    C, Contrast-enhanced T1-weighted axial MR image obtained 7 months later shows extension of leptomeningeal enhancement into subarachnoid space around anterior portions of left frontal and parietal lobes and perimesencephalic cistern (small arrows). Hydrocephalus was greater. Round low intensity in left posterior temporal calvarial region is owing to susceptibility artifact secondary to previous surgery (arrow).

    D, Contrast-enhanced T1-weighted sagittal MR image obtained another 7 months later shows more diffuse enhancement of almost entire subarachnoid space. Hydrocephalus disappeared after placement of ventriculoperitoneal shunt (not shown).

    E, Contrast-enhanced T1-weighted sagittal MR image of whole spine taken at same time as D shows diffuse leptomeningeal enhancement along surface of whole spinal cord and nerve roots (small arrows).

    F, Contrast-enhanced T1-weighted sagittal MR image 2 months after radiation therapy shows marked decrease of diffuse enhancement of subarachnoid space compared with that of figure D.

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Whal Lee, Kee-Hyun Chang, Gheeyoung Choe, Je G. Chi, Chun-Kee Chung, Il Han Kim, Moon Hee Han, Sun-Won Park, Sang June Shin, Young Hwan Koh
MR Imaging Features of Clear-Cell Meningioma with Diffuse Leptomeningeal Seeding
American Journal of Neuroradiology Jan 2000, 21 (1) 130-132;

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MR Imaging Features of Clear-Cell Meningioma with Diffuse Leptomeningeal Seeding
Whal Lee, Kee-Hyun Chang, Gheeyoung Choe, Je G. Chi, Chun-Kee Chung, Il Han Kim, Moon Hee Han, Sun-Won Park, Sang June Shin, Young Hwan Koh
American Journal of Neuroradiology Jan 2000, 21 (1) 130-132;
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