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Research ArticleBRAIN

Decreased BOLD Functional MR Activation of the Motor and Sensory Cortices Adjacent to a Glioblastoma Multiforme: Implications for Image-Guided Neurosurgery

Andrei I. Holodny, Michael Schulder, Wen Ching Liu, Joseph A. Maldjian and Andrew J. Kalnin
American Journal of Neuroradiology April 1999, 20 (4) 609-612;
Andrei I. Holodny
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Michael Schulder
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Wen Ching Liu
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Joseph A. Maldjian
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Andrew J. Kalnin
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Abstract

Summary: A patient with a glioblastoma multiforme and mild sensorimotor deficits had significantly less activation of the motor and sensory cortices on the side with the tumor than on the contralateral side on blood oxygen level–dependent (BOLD) functional MR images. This difference, which may be due to pressure effects or loss of vascular autoregulation, should be considered in preoperative planning in which BOLD functional MR imaging is used to identify eloquent cortices to be avoided during brain tumor surgery.

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American Journal of Neuroradiology
Vol. 20, Issue 4
1 Apr 1999
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Cite this article
Andrei I. Holodny, Michael Schulder, Wen Ching Liu, Joseph A. Maldjian, Andrew J. Kalnin
Decreased BOLD Functional MR Activation of the Motor and Sensory Cortices Adjacent to a Glioblastoma Multiforme: Implications for Image-Guided Neurosurgery
American Journal of Neuroradiology Apr 1999, 20 (4) 609-612;

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Decreased BOLD Functional MR Activation of the Motor and Sensory Cortices Adjacent to a Glioblastoma Multiforme: Implications for Image-Guided Neurosurgery
Andrei I. Holodny, Michael Schulder, Wen Ching Liu, Joseph A. Maldjian, Andrew J. Kalnin
American Journal of Neuroradiology Apr 1999, 20 (4) 609-612;
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Cited By...

  • Glioma-Induced Disruption of Resting-State Functional Connectivity and Amplitude of Low-Frequency Fluctuations in the Salience Network
  • A measure of vascular reactivity to overcome neurovascular uncoupling in functional imaging of brain tumors: initial results
  • Local Glioma Cells Are Associated with Vascular Dysregulation
  • Anatomic Location of Tumor Predicts the Accuracy of Motor Function Localization in Diffuse Lower-Grade Gliomas Involving the Hand Knob Area
  • Clinical applications of imaging biomarkers. Part 2. The neurosurgeon's perspective
  • Isolated Translocation of Wernicke's Area to the Right Hemisphere in a 62-Year-Man with a Temporo-Parietal Glioma
  • Imaging of intracranial tumours
  • Perimetric visual field and functional MRI correlation: implications for image-guided surgery in occipital brain tumours
  • The Effect of Brain Tumors on BOLD Functional MR Imaging Activation in the Adjacent Motor Cortex: Implications for Image-guided Neurosurgery
  • MEG versus BOLD MR Imaging: Functional Imaging, the Next Generation?
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