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  • Tumor cell-released autophagosomes (TRAPs) induce PD-L1-decorated NETs that suppress T-cell function to promote breast cancer pulmonary metastasis

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Basic tumor immunology
Original research
Tumor cell-released autophagosomes (TRAPs) induce PD-L1-decorated NETs that suppress T-cell function to promote breast cancer pulmonary metastasis

Authors

  • Xiaohe Zhou Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Microbiology and Immunology, School of Medicine, Southeast University, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Chengdong Wu Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Microbiology and Immunology, School of Medicine, Southeast University, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Xuru Wang Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Microbiology and Immunology, School of Medicine, Southeast University, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Ning Pan Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Microbiology and Immunology, School of Medicine, Southeast University, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Xiaotong Sun Department of Laboratory Medicine, Yantai Yuhuangding Hospital, Yantai, Shandong, China PubMed articlesGoogle scholar articles
  • Bohao Chen Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Microbiology and Immunology, School of Medicine, Southeast University, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Shiya Zheng Department of Oncology, Southeast University Zhongda Hospital, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Yiting Wei Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Microbiology and Immunology, School of Medicine, Southeast University, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Jing Chen Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Microbiology and Immunology, School of Medicine, Southeast University, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Yuyang Wu Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Microbiology and Immunology, School of Medicine, Southeast University, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Fengjiao Zhu Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Microbiology and Immunology, School of Medicine, Southeast University, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Jinpeng Chen Department of general surgery, Southeast University Zhongda Hospital, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles
  • Huabiao Chen Institute of Biomedical Engineering and Technology, School of Medicine, Ningbo University, Ningbo, China PubMed articlesGoogle scholar articles
  • Li-xin Wang Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Microbiology and Immunology, School of Medicine, Southeast University, Nanjing, Jiangsu, China PubMed articlesGoogle scholar articles

Citation

Zhou X, Wu C, Wang X, et al
Tumor cell-released autophagosomes (TRAPs) induce PD-L1-decorated NETs that suppress T-cell function to promote breast cancer pulmonary metastasis
Journal for ImmunoTherapy of Cancer 2024;12:e009082. doi: 10.1136/jitc-2024-009082
Online issue publication 
June 26, 2024

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.