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Immune cell therapies and immune cell engineering
Original research
ScRNA-seq reveals novel immune-suppressive T cells and investigates CMV-TCR-T cells cytotoxicity against GBM

Authors

  • Xinmiao Long Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, ChinaThe Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, ChinaFuRong Laboratory, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Zuping Zhang Department of Pathogeny Biology, School of Basic Medical Science, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Yuzhe Li Department of Neurosurgery in Xiangya Hospital, Central South University, Changsha, Hunan, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Peking University, Beijing, China PubMed articlesGoogle scholar articles
  • Kun Deng Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, ChinaThe Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, ChinaFuRong Laboratory, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Wei Gao Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, ChinaThe Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, ChinaFuRong Laboratory, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Meng Huang Department of Neurosurgery in Xiangya Hospital, Central South University, Changsha, Hunan, ChinaGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China Medical Research Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China PubMed articlesGoogle scholar articles
  • Xiangyu Wang Department of Neurosurgery in Xiangya Hospital, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Xiang Lin Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, ChinaThe Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Xiaoling She Department of Pathology in Second Xiangya Hospital, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Yiming Zhao Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, ChinaDepartment of Pathogeny Biology, School of Basic Medical Science, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Minfu Zhang Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Cheng Huang The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, ChinaFuRong Laboratory, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Shiyi Wang The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, ChinaFuRong Laboratory, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Yinfei Du The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, ChinaFuRong Laboratory, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Peng Du Department of Neurosurgery, The Second Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang, China PubMed articlesGoogle scholar articles
  • Shuai Chen Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Qing Liu Department of Neurosurgery in Xiangya Hospital, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles
  • Minghua Wu Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, ChinaThe Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, ChinaFuRong Laboratory, Central South University, Changsha, Hunan, China PubMed articlesGoogle scholar articles

Citation

Long X, Zhang Z, Li Y, et al
ScRNA-seq reveals novel immune-suppressive T cells and investigates CMV-TCR-T cells cytotoxicity against GBM
Journal for ImmunoTherapy of Cancer 2024;12:e008967. doi: 10.1136/jitc-2024-008967
Online issue publication 
April 30, 2024

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.