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Immunotherapy biomarkers
Original research
Ascites and resistance to immune checkpoint inhibition in dMMR/MSI-H metastatic colorectal and gastric cancers

Authors

  • Giovanni Fucà Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy PubMed articlesGoogle scholar articles
  • Romain Cohen Sorbonne Université, Department of Medical Oncology, Hôpital Saint-Antoine, AP-HP and INSERM, Unité Mixte de Recherche Scientifique 938, Centre de Recherche Saint-Antoine, Equipe Instabilité des Microsatellites et Cancer, Equipe labellisée par la Ligue Nationale contre le Cancer, Paris, France PubMed articlesGoogle scholar articles
  • Sara Lonardi Medical Oncology 3 and Medical Oncology 1, Istituto Oncologico Veneto IOV-IRCSS, Padua, Italy PubMed articlesGoogle scholar articles
  • Kohei Shitara Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan PubMed articlesGoogle scholar articles
  • Maria Elena Elez Department of Medical Oncology, Vall d'Hebron Barcelona Hospital Campus, Vall d'Hebron Institute of Oncology (VHIO), Universitat Autonoma de Barcelona, Barcelona, Spain PubMed articlesGoogle scholar articles
  • Marwan Fakih Department of Medical Oncology and Therapeutic Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA PubMed articlesGoogle scholar articles
  • Joseph Chao Department of Medical Oncology and Therapeutic Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA PubMed articlesGoogle scholar articles
  • Samuel J Klempner Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USAHarvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Matthew Emmett Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USAHarvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Priya Jayachandran Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Francesca Bergamo Medical Oncology 1, Istituto Oncologico Veneto IOV-IRCSS, Padua, Italy PubMed articlesGoogle scholar articles
  • Marc Díez García Department of Medical Oncology, Vall d'Hebron Barcelona Hospital Campus, Vall d'Hebron Institute of Oncology (VHIO), Universitat Autonoma de Barcelona, Barcelona, Spain PubMed articlesGoogle scholar articles
  • Giacomo Mazzoli Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy PubMed articlesGoogle scholar articles
  • Leonardo Provenzano Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy PubMed articlesGoogle scholar articles
  • Raphael Colle Sorbonne Université, Department of Medical Oncology, Hôpital Saint-Antoine, AP-HP and INSERM, Unité Mixte de Recherche Scientifique 938, Centre de Recherche Saint-Antoine, Equipe Instabilité des Microsatellites et Cancer, Equipe labellisée par la Ligue Nationale contre le Cancer, Paris, France PubMed articlesGoogle scholar articles
  • Magali Svrcek Sorbonne Université, Department of Pathology, Hôpital Saint-Antoine, AP-HP, and INSERM, Unité Mixte de Recherche Scientifique 938, Centre de Recherche Saint-Antoine, Equipe Instabilité des Microsatellites et Cancer, Equipe labellisée par la Ligue Nationale contre le Cancer, Paris, France PubMed articlesGoogle scholar articles
  • Margherita Ambrosini Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy PubMed articlesGoogle scholar articles
  • Giovanni Randon Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy PubMed articlesGoogle scholar articles
  • Aakash Tushar Shah Baylor College of Medicine, Houston, Texas, USA PubMed articlesGoogle scholar articles
  • Massimiliano Salati Division of Oncology, Department of Oncology and Hematology, University Hospital of Modena, PhD Clinical and Experimental Medicine (CEM), University of Modena and Reggio Emilia, Modena, Italy PubMed articlesGoogle scholar articles
  • Elisabetta Fenocchio Multidisciplinary Outpatient Oncology Clinic, Candiolo Cancer Institute FPO-IRCCS, Candiolo, Italy PubMed articlesGoogle scholar articles
  • Lisa Salvatore Department of Medical Oncology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy PubMed articlesGoogle scholar articles
  • Keigo Chida Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan PubMed articlesGoogle scholar articles
  • Akihito Kawazoe Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan PubMed articlesGoogle scholar articles
  • Veronica Conca Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, ItalyDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy PubMed articlesGoogle scholar articles
  • Giuseppe Curigliano European Institute of Oncology (IEO), IRCCS, Milan, ItalyDepartment of Oncology and Hemato-oncology, University of Milan, Milan, Italy PubMed articlesGoogle scholar articles
  • Francesca Corti Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy PubMed articlesGoogle scholar articles
  • Chiara Cremolini Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, ItalyDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy PubMed articlesGoogle scholar articles
  • Michael Overman Department of Gastrointestinal Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articlesGoogle scholar articles
  • Thierry Andre Sorbonne Université, Department of Medical Oncology, Hôpital Saint-Antoine, AP-HP and INSERM, Unité Mixte de Recherche Scientifique 938, Centre de Recherche Saint-Antoine, Equipe Instabilité des Microsatellites et Cancer, Equipe labellisée par la Ligue Nationale contre le Cancer, Paris, France PubMed articlesGoogle scholar articles
  • Filippo Pietrantonio Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy PubMed articlesGoogle scholar articles

Citation

Fucà G, Cohen R, Lonardi S, et al
Ascites and resistance to immune checkpoint inhibition in dMMR/MSI-H metastatic colorectal and gastric cancers
Journal for ImmunoTherapy of Cancer 2022;10:e004001. doi: 10.1136/jitc-2021-004001
Online issue publication 
October 18, 2023

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.