Germline biomarkers predict toxicity to anti-PD1/PDL1 checkpoint therapy

Joanne Weidhaas; Nicholas Marco; Aaron W Scheffler; Anusha Kalbasi; Kirk Wilenius; Emily Rietdorf; Jaya Gill; Mara Heilig; Caroline Desler; Robert K Chin; Tania Kaprealian; Susan McCloskey; Ann Raldow; Naga P Raja; Santosh Kesari; Jose Carrillo; Alexandra Drakaki; Mark Scholz; Donatello Telesca

doi:10.1136/jitc-2021-003625

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Immunotherapy biomarkers

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Germline biomarkers predict toxicity to anti-PD1/PDL1 checkpoint therapy

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Joanne Weidhaas Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Nicholas Marco Department of Biostatistics, UCLA, Los Angeles, California, USA PubMed articles Google scholar articles
Aaron W Scheffler Department of Biostatistics, UCLA, Los Angeles, California, USA PubMed articles Google scholar articles
Anusha Kalbasi Department of Biostatistics, UCLA, Los Angeles, California, USA PubMed articles Google scholar articles
Kirk Wilenius Prostate Oncology Specialists, Marina Del Rey, California, USA PubMed articles Google scholar articles
Emily Rietdorf Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Jaya Gill Pacific Neuroscience Institute and Saint John’s Cancer Institute, Santa Monica, California, USA PubMed articles Google scholar articles
Mara Heilig Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Caroline Desler Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Robert K Chin Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Tania Kaprealian Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Susan McCloskey Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Ann Raldow Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Naga P Raja Appalachian Regional Healthcare, Hazard, Kentucky, USA PubMed articles Google scholar articles
Santosh Kesari Pacific Neuroscience Institute and Saint John’s Cancer Institute, Santa Monica, California, USA PubMed articles Google scholar articles
Jose Carrillo Pacific Neuroscience Institute and Saint John’s Cancer Institute, Santa Monica, California, USA PubMed articles Google scholar articles
Alexandra Drakaki Department of Urology, Medical Oncology, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Mark Scholz Prostate Oncology Specialists, Marina Del Rey, California, USA PubMed articles Google scholar articles
Donatello Telesca Department of Biostatistics, UCLA, Los Angeles, California, USA PubMed articles Google scholar articles

Citation

Weidhaas J, Marco N, Scheffler AW, et al

Germline biomarkers predict toxicity to anti-PD1/PDL1 checkpoint therapy

Journal for ImmunoTherapy of Cancer 2022;10:e003625. doi: 10.1136/jitc-2021-003625

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October 18, 2023

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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