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897-F Wnt inhibition improves efficacy of immune checkpoint blockade in glioblastoma
Shanmugarajan Krishnan, Somin Lee, Zohreh Amoozgar, Sonu Subudhi, Ashwin Srinivasan Kumar, Jessica Posada, Neal I Lindeman, Pinji Lei, Mark Duquette, Sylvie Roberge, Peigen Huang, Patrik Andersson, Meenal Datta, Lance L Munn, Dai Fukumura, Rakesh K Jain

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 2) A1824-A1825; DOI: 10.1136/jitc-2023-SITC2023.0897-F
897-G SR-8541A, a small molecule inhibitor of ENPP1, enhances the effect of immune checkpoint inhibitors in a colorectal cancer model
Alexis Weston, Trason Thode, Serina Ng, Tithi Ghosh-Halder, Katelyn Gutowsky, Brian Durbin, Raffaella Soldi, Monil Shah, Jonathan Northrup, Srinivas Kasibhatla, Mohan Kaadige, Sunil Sharma

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 2) A1826; DOI: 10.1136/jitc-2023-SITC2023.0897-G
1040-A Leptin reprograms the macrophage response to inflammatory mediators: link between metabolism and immunity in obesity
Bowen Dong, Spencer Rosario, Adam Brinkman, Ronald Slomba, Yali Zhang, Jianmin Wang, Sarbajit Mukherjee, Pawel Kalinski

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 2) A1827; DOI: 10.1136/jitc-2023-SITC2023.1040-A
1040-B Identifying tumor-associated antigens in different stages of multiple myeloma using low input HLA immunopeptidomics
Gabrielle M Hernandez, Hannah Taylor, Eva K Verzani, Claudia Ctortecka, David A Berrios Nolasco, Karl R Clauser, Namrata D Udeshi, Jennifer G Abelin, Elisabet Manasanch, Steven A Carr

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 2) A1828; DOI: 10.1136/jitc-2023-SITC2023.1040-B
1040-C A novel subset of granulocytic MDSCs expressing PD-1 as immunosuppressive regulators and therapeutic targets in gastric cancer
Kazunori Kato, Takumi Iwasawa, Suguru Yamauchi, Tetsu Fukunaga, Hajime Orita

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 2) A1829; DOI: 10.1136/jitc-2023-SITC2023.1040-C
1040-D Identification of four clinically-relevant immunomodulatory programs shared across nearly all glioma-associated myeloid cells
Tyler E Miller, Chadi El Farran, Charles Couturier, Zeyu Chen, Joshua D’Antonio, Alex Shalek, Kevin Petrecca, Mario Suva, Bradley Bernstein

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 2) A1830; DOI: 10.1136/jitc-2023-SITC2023.1040-D
1040-E Deciphering and targeting the schwannoma-neuron-macrophage crosstalk for the treatment of schwannomatosis and associated pain
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, John W Chen, Sonu Subudhi, Grace Lee, Athena Wang, Xing Gao, Jun Ren, Alona Muzikansky, Anat Stemmer-Rachamimov, Jianren Mao, Scott R Plotkin, Lei Xu

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 2) A1831; DOI: 10.1136/jitc-2023-SITC2023.1040-E
1040-F Novel phytochemicals-based media supports NK cell expansion using neither feeder cells nor IL-2, while achieving high cytotoxicity against cancer cells
Matthew Forsberg, Ankita Shahi De, Marc A Gillig, Rachit Ohri, Christian Capitini

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 2) A1832; DOI: 10.1136/jitc-2023-SITC2023.1040-F
1040-G Novel phytochemicals-based media (added as a supplement) improves the exhaustion and activation phenotype of NK cells cultured in commercially available NK cell media
Marc A Gillig, Nicholas Ingala, Karissa Mennes, Borom Chean, Mirok German, Jeffrey Bowler, Rachit Ohri

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 2) A1833; DOI: 10.1136/jitc-2023-SITC2023.1040-G
1040-H Coupling DNA barcoding and multi-peptide screening: unveiling T cell receptor and antigenic peptide relationships in complex samples
Xiaohong Hou, Yuri Poluektov, Wenjing Pan, Emily Sims, Miranda Byrne-Steele, Marc Delcommenne

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 2) A1834; DOI: 10.1136/jitc-2023-SITC2023.1040-H

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