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961 Tumor-infiltrating lymphocytes in tumor microenvironment assessed by artificial intelligence powered H&E image analyzer is correlated with immunomodulatory subtype of triple-negative breast cancer
Jimin Moon, Chang Ho Ahn, Seunghwan Shin, Seulki Kim, Taebum Lee, Soo Ick Cho, Yoojoo Lim, Mingu Kang, Heon Song, Donggeun Yoo, Ken Nesmith, Siraj Ali, Chan-Young Ock, Seokhwi Kim

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) 1068; DOI: 10.1136/jitc-2023-SITC2023.0961
104 A spatial pharmacology approach to decipher drug-target-microenvironment interactions in situ
Guolan Lu, Garry Nolan, Eben Rosenthal

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) 118; DOI: 10.1136/jitc-2023-SITC2023.0104
1096 A novel viral immunotherapeutic targeting the CD47/SIRPα axis demonstrates potent anti-tumor effects
Anne R Diers, Qiuchen Guo, John D Christie, David Krisky, Paul P Tak, Francesca Barone

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) 1205; DOI: 10.1136/jitc-2023-SITC2023.1096
1108 Novel regulators of ImmTAC-mediated killing of melanoma cancer cells revealed by genome-wide CRISPR-Cas9 screens
Aleksandra Raczka, Sophie Khakoo, Shankar Varadarajan, James Clubley, Laura Collins, Koustubh Ranade, Adel Benlahrech

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) 1220; DOI: 10.1136/jitc-2023-SITC2023.1108
1324 The effect of antibiotic therapy on immunotherapy outcomes in the treatment of acquired bacterial infections during stage IV cancer treatment
Ernest Philon, Daniel Johnson, Wesley Duerson, Graham Unis

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) 1475; DOI: 10.1136/jitc-2023-SITC2023.1324
134 mNTX-250, a novel multimodal HPV-16 mRNA-based therapeutic, induces potent anti-tumor responses and establishes HPV-16 specific immune memory
Ou Li, Nicole Fay, Diane Da Silva, Ruben Prin, Daniel Fernandez, Stephanie Wong, Zhang-Xu Liu, Martin Kast, Rob Schott

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) 154; DOI: 10.1136/jitc-2023-SITC2023.0134
1468 Peptide vaccination against PD-L1 reduces tumor growth in preclinical models through stimulation of PD-L1-targeting T cells in the tumor microenvironment
Marion Chapellier, Marco Carretta, Erika Sutanto-Ward, James DuHadaway, Souvik Dey, Dema Ghaban, Preeyam Patel, Marcos Iglesias, Qin Tang, Megan Biller, Ines Lecoq, Lea Svendsen, Evelina Martinenaite, Alexander J Muller, Ayako Pedersen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) 1632; DOI: 10.1136/jitc-2023-SITC2023.1468
1506 Comprehensive assessment of lymphocyte counts in colorectal cancer: Defining the optimal prognostic marker
Patrick Wagner, Jianwu Xie, Neda Dadgar, Devin C Flaherty, Louis Gil Acevedo, William A LaFramboise, Kunhong Kevin Xiao, Curtis Tilves, Justine Debelius, Ni Zhao, Cynthia Sears, Noel Mueller

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) 1670-1671; DOI: 10.1136/jitc-2023-SITC2023.1506
173 Deciphering the tumor microenvironment of renal cell carcinoma: integrating single-cell sequencing and In Situ spatial transcriptomics for comprehensive characterization of tumor-infiltrating T cells
Heeju Ryu, David Glass, Azadeh Hadadianpour, Daniel C Jones, Long T Nguyen, Ernest Moelhman, Fiona Pakiam, Jack Johanneson, Anna Elz, Michelle A Wurscher, Korok Sarkar, Joshua X Yee, Evan Newell

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) 197; DOI: 10.1136/jitc-2023-SITC2023.0173
242 Anti-B7H3 chimeric antigen receptor NK cells for high-risk pediatric brain tumors
Jun Choe, Sachiv Chakravarti, Natalie Holl, Arjun Modi, Ruyan Rahnama, Stamatia Vorri, Eric H Raabe, Challice L Bonifant

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) 279; DOI: 10.1136/jitc-2023-SITC2023.0242

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