topic

239 CSPG4-targeted CAR T cells demonstrate potent antitumor activity in an orthotopic murine model of anaplastic thyroid cancer
Giulia Cattaneo, Marco Ventin, Venkata Rao Vantaku, Shahrzad Arya, Jingyu Jia, Luke Maggs, Xinhui Wang, Sareh Parangi, Cristina R Ferrone, Soldano Ferrone

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A275; DOI: 10.1136/jitc-2023-SITC2023.0239
240 Presentation of DLL4 and VCAM on paramagnetic beads replicates thymic Notch signaling and enables differentiation of functional of iPSC derived TCR T-cells in vitro
Siddarth Chandrasekaran, Melanie Kardel, Elisa Martinez, Nabil Zeidan, Avisek Deyati, Valerie Wall, Dylan Lee, Negin Farahani, Amanda AuYeung, Omar Subedar, Michael Cadell, Sommer Apelu, Laura Prochazka, Zahra Sahaf, Angela Duong, Cole Zmurchok, Boyoung Yoon, Dan Kirouac, Muluken Belew, Jasdeep Mann, Deepika Rajesh, Chris Bond

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A276; DOI: 10.1136/jitc-2023-SITC2023.0240
241 Abstract withdrawn
Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A277-A278; DOI: 10.1136/jitc-2023-SITC2023.0241
243 Efficient generation of CD8⁺ T_SCM CD19 chimeric antigen receptor T-cells (CAR-T cells) by treatment with novel cytokine-based scaffolds
Erin Cole, Moriah Rabin, Niraj Shrestha, Jian Hua Zheng, Hing C Wong, Harris Goldstein

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A280-A282; DOI: 10.1136/jitc-2023-SITC2023.0243
244 Targeting gangliosides in pediatric cancer
Guillermo N Dalton, Won-Ju Kim, Nathaniel W Mabe, Min Huang, Maria Caterina Rotiroti, Aidan M Tousley, Kimberly Stegmaier, Robbie G Majzner

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A283; DOI: 10.1136/jitc-2023-SITC2023.0244
245 Development and application of physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model for dose optimization of TAK-102: GPC3 targeted CAR-T armored with IL-7 and CCL-19
Agnish Dey, Hideaki Kagehara, Petar Pop-Damkov, Eriko Sumi, Eiki Maeda, Takenori Akaike, Kondala Atkuri, Kotaro Suzuki, Masashi Ochi, Takafumi Koyama, Yasutoshi Kuboki, Takako Eguchi Nakajima, Ganesh M Mugundu, Aman Singh

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A284; DOI: 10.1136/jitc-2023-SITC2023.0245
246 Disruption of the cytokine signaling checkpoint CIS enhances serial-killing and anti-tumor activity of CAR-engineered γδ T cells
Beibei Ding, Melinda Au, Alex Teague, Logan Chinn, Yvan Chanthery, Blake T Aftab, Arun Bhat, Kevin P Nishimoto

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A285; DOI: 10.1136/jitc-2023-SITC2023.0246
247 FOXO1 is a master regulator of CAR T memory programming
Alexander E Doan, Katherine P Mueller, Andy Chen, Geoffrey Rouin, Bence Daniel, John Lattin, Yingshi Chen, Brett Mozarsky, Martina Markovska, Jose Arias-Umana, Robert Hapke, Inyoung Jung, Peng Xu, Dorota Klysz, Malek Bashti, Patrick Quinn, Katalin Sandor, Wenxi Zhang, Junior Hall, Caleb A Lareau, Stephan Grupp, Joseph A Fraietta, Elena Sotillo, Ansuman T Satpathy, Crystal L Mackall, Evan W Weber

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A286; DOI: 10.1136/jitc-2023-SITC2023.0247
248 SMART CAR-T cells resist tumor immunosuppressive microenvironment with enhanced efficacy against solid tumors
Qi Dong, Wenjie Yin, Manli Yin, Tao Wang, Di Wu, Xinxin Wang, William Cao, Lianjun Shen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A287; DOI: 10.1136/jitc-2023-SITC2023.0248
249 Vascular normalization improves the delivery and efficacy of EGFRvIII-CAR-T cells in mouse glioblastoma
Xinyue Dong, Jun Ren, Zohreh Amoozgar, Somin Lee, Meenal Datta, Sylvie Roberge, Mark Duquette, Dai Fukumura, Rakesh K Jain

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A288; DOI: 10.1136/jitc-2023-SITC2023.0249

Main menu

topic

Pages

Log in using your username and password

Main menu

Log in using your username and password

You are here

topic

Pages