Basic Tumor Immunology

Chemotherapy accelerates immune-senescence and functional impairments of Vδ2^pos T cells in elderly patients affected by liver metastatic colorectal cancer
Elena Bruni, Valentina Cazzetta, Matteo Donadon, Matteo Cimino, Guido Torzilli, Gianmarco Spata, Gloria Leonardi, Francesco Dieli, Joanna Mikulak, Domenico Mavilio

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 347; DOI: 10.1186/s40425-019-0825-4
Genetic instability as a driver for immune surveillance
Guim Aguadé-Gorgorió, Ricard Solé

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 345; DOI: 10.1186/s40425-019-0795-6
miR-448 targets IDO1 and regulates CD8⁺ T cell response in human colon cancer
Qiong Lou, Ruixian Liu, Xiangling Yang, Weiqian Li, Lanlan Huang, Lili Wei, Huiliu Tan, Nanlin Xiang, Kawo Chan, Junxiong Chen, Huanliang Liu

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 210; DOI: 10.1186/s40425-019-0691-0
Blocking CD47 efficiently potentiated therapeutic effects of anti-angiogenic therapy in non-small cell lung cancer
Xuyao Zhang, Yichen Wang, Jiajun Fan, Wei Chen, Jingyun Luan, Xiaobin Mei, Shaofei Wang, Yubin Li, Li Ye, Song Li, Wenzhi Tian, Kai Yin, Dianwen Ju

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 346; DOI: 10.1186/s40425-019-0812-9
Endocrine toxicity of immune checkpoint inhibitors: a real-world study leveraging US Food and Drug Administration adverse events reporting system
Yinghong Zhai, Xiaofei Ye, Fangyuan Hu, Jinfang Xu, Xiaojing Guo, Yonglong Zhuang, Jia He

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 286; DOI: 10.1186/s40425-019-0754-2
Efficacy of PD-1 blockade in cervical cancer is related to a CD8⁺FoxP3⁺CD25⁺ T-cell subset with operational effector functions despite high immune checkpoint levels
A. M. Heeren, J. Rotman, A. G. M. Stam, N. Pocorni, A. A. Gassama, S. Samuels, M. C. G. Bleeker, C. H. Mom, H. J. M. A. A. Zijlmans, G. G. Kenter, E. S. Jordanova, T. D. de Gruijl

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 43; DOI: 10.1186/s40425-019-0526-z
PD-1 signaling affects cristae morphology and leads to mitochondrial dysfunction in human CD8⁺ T lymphocytes
Jesús Ogando, María Eugenia Sáez, Javier Santos, Cristina Nuevo-Tapioles, Marta Gut, Anna Esteve-Codina, Simon Heath, Antonio González-Pérez, José M. Cuezva, Rosa Ana Lacalle, Santos Mañes

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 151; DOI: 10.1186/s40425-019-0628-7
Development of a new fusion-enhanced oncolytic immunotherapy platform based on herpes simplex virus type 1
Suzanne Thomas, Linta Kuncheria, Victoria Roulstone, Joan N. Kyula, David Mansfield, Praveen K. Bommareddy, Henry Smith, Howard L. Kaufman, Kevin J. Harrington, Robert S. Coffin

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 214; DOI: 10.1186/s40425-019-0682-1
Distinct tumor microenvironments of lytic and blastic bone metastases in prostate cancer patients
Claire L. Ihle, Meredith D. Provera, Desiree M. Straign, E. Erin Smith, Susan M. Edgerton, Adrie Van Bokhoven, M. Scott Lucia, Philip Owens

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 293; DOI: 10.1186/s40425-019-0753-3
NKG2D signaling certifies effector CD8 T cells for memory formation
Cynthia Perez, Kushal Prajapati, Brianna Burke, Lourdes Plaza-Rojas, Nancy J. Zeleznik-Le, Jose A. Guevara-Patino

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 48; DOI: 10.1186/s40425-019-0531-2

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