- Intravoxel Incoherent Motion MR Imaging in the Differentiation of Benign and Malignant Sinonasal Lesions: Comparison with Conventional Diffusion-Weighted MR Imaging
One hundred thirty-one patients with histologically proved solid sinonasal lesions (56 benign and 75 malignant) who underwent conventional DWI and intravoxel incoherent motion were evaluated. The diffusion coefficient (D), pseudodiffusion coefficient (D*), and perfusion fraction (f) values derived from intravoxel incoherent motion and ADC values derived from conventional DWI were measured and compared. The mean ADC and D values were significantly lower in malignant sinonasal lesions than in benign sinonasal lesions and the mean f value was higher in malignant than in benign lesions. Multiparametric models can significantly improve the cross-validated areas under the curve for the differentiation of sinonasal lesions compared with single-parametric models. The authors conclude that intravoxel incoherent motion appears to be a more effective MR imaging technique than conventional DWI in the differentiation of benign and malignant sinonasal lesions.
- Lymphographic-Like Technique for the Treatment of Microcystic Lymphatic Malformation Components of <3 mm
A retrospective analysis of a prospectively collected lymphatic malformation data base was performed that included 16 patients (5 males, 11 females; mean age, 15 years; range, 1=47 years). Patients with at least 1 microcystic lymphatic malformation component demonstrated on MR imaging treated by lymphographic-like technique bleomycin infusion were included in the study. Patient interviews and MR imaging were performed to assess subjective and objective clinical improvement (microcystic lymphatic malformation size decrease of >30%). The authors observed no major and 3 minor complications: 1 eyelid infection, 1 case of severe postprocedural nausea and vomiting, and 1 case of skin discoloration. MR imaging objective improvement was observed in 5/16 (31%) patients; overall improvement of clinical symptoms was obtained in 93% of treated patients. Bleomycin lymphographic-like technique for microcystic lymphatic malformations was safe and feasible with objective improvement in about one-third of patients.
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