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This review article summarizes the key concepts related to pericarotid fat and its pathophysiology, examining its applicability as noninvasive imaging of plaque vulnerability and cerebrovascular events.

Cancer-associated hypercoagulability-related stroke is presumably caused by fibrin-predominant thrombi and is associated with the absence of the susceptibility vessel sign (sensitivity of 90%/specificity of 78%/ likelihood ratio of 4.06). This is in contradistinction to cardioembolic erythrocyte-predominant thrombi, which demonstrate hypointense signal on T2-weighted gradient-recalled echo images (susceptibility vessel sign).