- Prospective Comparison of Angio-Seal versus Manual Compression for Hemostasis after Neurointerventional Procedures under Systemic Heparinization
This article addresses the utility of Angio-Seal versus manual hemostasis in anticoagulated patients following neurointerventional procedures. In a study of 174 punctures, 104 were closed with Angio-Seal and the rest with manual compression. All patients had activated clotting time values between 250–500 seconds at the time of closure. Mean hemostasis times were significantly longer with manual compression and hematomas 3 times more common. Using Angio-Seal led to arterial occlusion in 1 patient who was successfully revascularized. Thus, Angio-Seal is fast and effective in this setting.
- Factors Influencing Clinically Meaningful Recanalization after IV-rtPA in Acute Ischemic Stroke
Predictors of clinically meaningful recanalization were assessed in 126 patients with acute anterior circulation stroke treated with IV thrombolysis. End points were CT angiographic recanalization and good clinical outcome at 90 days. Clinically meaningful recanalization occurred in 29% of patients, who had fewer neurologic deficits and higher ASPECTS at baseline. Admission NIHSS score and site of arterial occlusion were significant predictors of meaningful recanalization. Specifically, mild baseline deficits and distal vessel occlusions were significant predictors of clinically meaningful recanalization. A combination of these was better than either parameter alone.
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