- Single Large-Scale Mitochondrial Deletion Syndromes: Neuroimaging Phenotypes and Longitudinal Progression in Pediatric Patients
This retrospective observational study is a longitudinal analysis of the neuroimaging pattern of single large-scale mitochondrial deletion syndrome, which is often classified into 3 major clinical syndromes: Kearns-Sayre syndrome, chronic progressive external ophthalmoplegia, and Pearson syndrome. Early findings typically involve the brainstem and basal ganglia with the supratentorial subcortical white matter changes and spinal cord involvement as the disease progresses.
- A Review of Intracranial Aneurysm Imaging Modalities, from CT to State-of-the-Art MR
This review article covers the established imaging modalities (eg, CT, CTA, DSA, FLAIR, 3D TOF-MRA, contrast-enhanced MRA) and novel MR techniques (MR vessel wall imaging, dynamic contrast-enhanced MRI, computational fluid dynamics) of intracranial aneurysm evaluation. Artificial intelligence software and its integration into diagnostic and risk-stratification pipelines for intracranial aneurysms are also discussed.
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