- Temporal Changes on Postgadolinium MR Vessel Wall Imaging Captures Enhancement Kinetics of Intracranial Atherosclerotic Plaques and Aneurysms
MR VWI in patients with symptomatic intracranial atherosclerotic disease plaques and aneurysms showed contrast accumulation beyond the early-phase (5–15 min) into the delayed phase (20–30 min). This nonspecific enhancement may indicate focal inflammation, neoangiogenesis, and/or increased permeability. The authors advocate postcontrast imaging soon after contrast administration to optimize diagnostic accuracy.
- An Optimized CT Protocol for Detecting Suspected Cauda Equina Syndrome: A Comparative Analysis with MRI
This study prospectively evaluated the diagnostic accuracy of an optimized CT lumbar spine protocol as a potential alternative to MRI in assessing suspected neural compression. CT accurately identified all cases requiring urgent decompression. CT had 97% sensitivity, specificity, and positive and negative predictive values in detecting disc pathology in patients presenting with symptoms suggestive of acute neural compression compared with MRI.
- Risk of Hemorrhagic Transformation after Mechanical Thrombectomy without versus with IV Thrombolysis for Acute Ischemic Stroke: A Systematic Review and Meta-analysis of Randomized Clinical Trials
This systematic review and meta-analysis evaluated the risk of intracerebral hemorrhage, and its subtypes associated with mechanical thrombectomy with or without IV thrombolysis for the treatment of acute ischemic stroke due to large-vessel occlusion. The analysis showed that the overall risk of symptomatic intracerebral hemorrhage was comparable between mechanical thrombectomy with IV thrombolysis and mechanical thrombectomy alone.
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