- Hemorrhage Volume Drives Early Brain Injury and Outcome in Poor-Grade Aneurysmal SAH
Early brain injury (radiologically defined by global cerebral edema) is a major determinant of clinical outcome in poor-grade aneurysmal SAH. In this retrospective study of 400 patients with poor-grade aneurysmal SAH, it was shown that intracerebral hemorrhage volume independently predicted global cerebral edema and long-term outcome, intraventricular hemorrhage volume predicted mortality and long-term outcome, and SAH volume predicted long-term clinical outcome.
- A Clinical and Imaging Fused Deep Learning Model Matches Expert Clinician Prediction of 90-Day Stroke Outcomes
The authors in this study used a deep learning-based predictive model (DLPD) that incorporated DWI and clinical data from the acute period to predict 90-day mRS outcomes and compared its predictions with those made by physicians. The results showed that the clinical and imaging fused deep learning model is noninferior to expert physicians in predicting specific mRS outcomes and unfavorable prognoses.
- Development of Collateral Vessels after Anterior Circulation Large Vessel Occlusion in Pediatric Arterial Ischemic Stroke Relates to Stroke Etiology: A Longitudinal Study
In this single-center retrospective study of pediatric patients with acute AIS related to anterior circulation proximal LVO, a specific pattern of unilateral poststroke anastomotic bridge with collaterals bypassing the affected zone was observed in the first year after stroke. This clinical-radiologic pattern was not associated with stroke recurrence or arterial worsening but was strongly associated with focal cerebral arteriopathy.
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