- Glial Fibrillary Acidic Protein Astrocytopathy: Review of Pathogenesis, Imaging Features, and Radiographic Mimics
Glial fibrillary acidic protein (GFAP) astrocytopathy is a CNS autoimmune inflammatory disorder characterized by specific antibodies targeting the intracellular filament protein in mature astrocytes. Neuroimaging findings include linear perivascular enhancement in the white matter extending in a radial pattern, periependymal enhancement, longitudinally extensive cord signal changes, intramedullary enhancement, optic neuritis, and papillitis.
- Retrolabyrinthine Bone Thickness as a Radiologic Marker for the Hypoplastic Endotype in Menière Disease
There are 2 major endotypes of Menière disease: one with a hypoplastic, underdeveloped endolymphatic sac and one with a normally developed sac that degenerates over time. This study explored the link between angular trajectory of the vestibular aqueduct and the thickness of the retrolabyrinthine bone to provide differentiation between MD endotypes using CT and MRI. The average retrolabyrinthine bone thickness was statistically significantly different between endotypes with retrolabyrinthine bone thickness >=1.2 mm, effectively ruling out hypoplastic Menière disease.
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