- Stroke Thrombectomy for Large Infarcts with Limited Penumbra: Systematic Review and Meta-Analysis of Randomized Trials
This meta-analysis evaluated randomized clinical trial results to provide more definitive guidance on the role of EVT for patients with stroke with large infarcts based on perfusion metrics. The results showed that the effectiveness of thrombectomy is uncertain regarding the safety and efficacy of thrombectomy for patients with limited areas of at-risk tissue. EVT may be beneficial for those with intermediate perfusion mismatch (ratio of 1.2-1.8 or volume of 10-15 mL) but not for those with low perfusion mismatch (ratio <1.2 or volume <10 mL).
