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This systematic review of patients with middle ear sinonasal-type tumors with a history of primary sinonasal tumors shows a tumor pattern supporting the hypothesis that the Eustachian tube may facilitate the spread of sinonasal neoplasms from the sinonasal cavity to the temporal bone.

Early brain injury (radiologically defined by global cerebral edema) is a major determinant of clinical outcome in poor-grade aneurysmal SAH. In this retrospective study of 400 patients with poor-grade aneurysmal SAH, it was shown that intracerebral hemorrhage volume independently predicted global cerebral edema and long-term outcome, intraventricular hemorrhage volume predicted mortality and long-term outcome, and SAH volume predicted long-term clinical outcome.