MY CONTENT

The “Spinal CSF Leak: Bridging the Gap” Conference highlighted collective insights from a diverse cohort of clinicians, researchers, and patients. This manuscript discusses the clinical, diagnostic, and treatment challenges of spinal CSF leak, concluding that a collaborative, multidisciplinary care team needs to provide a standardized-yet-flexible diagnostic protocol to address the variability in clinical presentations and often-subtle radiographic findings.

In this retrospective, single-center cohort study, 141 patients (173 lesions) with a new or increasing contrast-enhancing lesion after radiotherapy with or without chemotherapy were assessed with ASL perfusion. Although ASL performed poorly in differentiating progressive disease from treatment-induced effects in high-grade gliomas within 6 months after radiation therapy, it showed fair performance after this period.