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The purpose of this study was to investigate whether the shape (bilobed or indented appearance of the Meckel cave) or the size/volume of the Meckel cave on T2-weighted MRI could serve as a noninvasive diagnostic imaging marker for the diagnosis of idiopathic intracranial hypertension. The authors studied 75 patients with a diagnosis of IIH and 75 age-and sex-matched healthy controls. The transverse diameter of the Meckel cave was measured in the axial and coronal planes of T2-weighted MRI, and comparison was made between the 2 groups. Of 75 patients with an approved diagnosis of IIH, 57 (76%) showed an indented Meckel cave as opposed to 21 (28%) in the control group. They conclude that the shape and size of the Meckel cave can be used as sensitive and specific diagnostic imaging markers for the diagnosis of IIH.

The authors report a unique series of young patients with COVID-19 presenting with cerebral venous system thrombosis. Three patients younger than 41 years of age with confirmed Severe Acute Respiratory Syndrome coronavirus 2 infection had neurologic findings related to cerebral venous thrombosis.