- Hemodynamic Characteristics in Ruptured and Unruptured Intracranial Aneurysms: A Prospective Cohort Study Utilizing the AneurysmFlow Tool
A DSA-based flow quantification tool (AneurysmFlow) was used to measure blood flow vectors and velocities after contrast injection. Complex flow patterns were shown to be common in ruptured aneurysms and those with daughter sacs. Lowest mean aneurysm flow amplitude in the dome and daughter sacs indicated pathophysiologic changes linked to rupture. Also, hypertension, bifurcation location, and irregular shape of unruptured aneurysm were found to be independent rupture risk factors.
- Absence of the Susceptibility Vessel Sign with Cancer-Associated Hypercoagulability-Related Stroke
Cancer-associated hypercoagulability-related stroke is presumably caused by fibrin-predominant thrombi and is associated with the absence of the susceptibility vessel sign (sensitivity of 90%/specificity of 78%/ likelihood ratio of 4.06). This is in contradistinction to cardioembolic erythrocyte-predominant thrombi, which demonstrate hypointense signal on T2-weighted gradient-recalled echo images (susceptibility vessel sign).
