Immunotherapy

Machine learning-based integration develops a metabolism-derived consensus model for improving immunotherapy in pancreatic cancer
Yongdong Guo, Ronglin Wang, Jingjie Shi, Cheng Yang, Peixiang Ma, Jie Min, Ting Zhao, Lei Hua, Yang Song, Junqiang Li, Haichuan Su

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007466; DOI: 10.1136/jitc-2023-007466
RIG-I promotes immune evasion of colon cancer by modulating PD-L1 ubiquitination
Yangyang Zhang, Lingxiu Zeng, Meng Wang, Zhenwei Yang, Hailin Zhang, Liping Gao, Ranran Zhang, Jialong Liu, Wenqing Shan, Ying Chang, Lan Liu, Qiu Zhao, Yong Li, Jing Liu

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007313; DOI: 10.1136/jitc-2023-007313
Identification of neoepitope reactive T-cell receptors guided by HLA-A*03:01 and HLA-A*11:01 immunopeptidomics
Catherine M Ade, Matthew J Sporn, Sudipto Das, Zhiya Yu, Ken-ichi Hanada, Yue A Qi, Tapan Maity, Xu Zhang, Udayan Guha, Thorkell Andresson, James C Yang

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007097; DOI: 10.1136/jitc-2023-007097
KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response
Casey R Ager, Mingxuan Zhang, Matthew Chaimowitz, Shruti Bansal, Somnath Tagore, Aleksandar Obradovic, Collin Jugler, Meri Rogava, Johannes C Melms, Patrick McCann, Catherine Spina, Charles G Drake, Matthew C Dallos, Benjamin Izar

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e006782; DOI: 10.1136/jitc-2023-006782
Antitumor activity of the investigational B7-H3 antibody-drug conjugate, vobramitamab duocarmazine, in preclinical models of neuroblastoma
Chiara Brignole, Enzo Calarco, Veronica Bensa, Elena Giusto, Patrizia Perri, Eleonora Ciampi, Maria Valeria Corrias, Simonetta Astigiano, Michele Cilli, Derik Loo, Ezio Bonvini, Fabio Pastorino, Mirco Ponzoni

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007174; DOI: 10.1136/jitc-2023-007174
Targeting T-cell malignancies using allogeneic double-negative CD4-CAR-T cells
Karen Kai-Lin Fang, Jongbok Lee, Ismat Khatri, Yoosu Na, Li Zhang

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007277; DOI: 10.1136/jitc-2023-007277
Fibroblast growth factor receptor 3 mutation attenuates response to immune checkpoint blockade in metastatic urothelial carcinoma by driving immunosuppressive microenvironment
Yuxuan Song, Yun Peng, Caipeng Qin, Yulong Wang, Wenbo Yang, Yiqing Du, Tao Xu

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e006643; DOI: 10.1136/jitc-2022-006643
Synergic prognostic value of 3D CT scan subcutaneous fat and muscle masses for immunotherapy-treated cancer
Pierre Decazes, Samy Ammari, Younes Belkouchi, Léo Mottay, Littisha Lawrance, Antoine de Prévia, Hugues Talbot, Siham Farhane, Paul-Henry Cournède, Aurelien Marabelle, Florian Guisier, David Planchard, Tony Ibrahim, Caroline Robert, Fabrice Barlesi, Pierre Vera, Nathalie Lassau

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007315; DOI: 10.1136/jitc-2023-007315
Dynamical modeling of proliferative-invasive plasticity and IFNγ signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity
Seemadri Subhadarshini, Sarthak Sahoo, Shibjyoti Debnath, Jason A Somarelli, Mohit Kumar Jolly

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e006766; DOI: 10.1136/jitc-2023-006766
Inhibition of TCA cycle improves the anti-PD-1 immunotherapy efficacy in melanoma cells via ATF3-mediated PD-L1 expression and glycolysis
Nian Liu, Mingjie Yan, Qian Tao, Jie Wu, Jing Chen, Xiang Chen, Cong Peng

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007146; DOI: 10.1136/jitc-2023-007146

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