Immunotherapy

Letter to the editor: Hypoxia kinetics and histology in combined radiotherapy and oxidative phosphorylation inhibition effects on antitumor immunity
Daan F Boreel, Paul N Span, Johan Bussink

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001793; DOI: 10.1136/jitc-2020-001793
Chimeric antigen receptor engineered NK cellular immunotherapy overcomes the selection of T-cell escape variant cancer cells
Maxwell Y Lee, Yvette Robbins, Cem Sievers, Jay Friedman, Houssein Abdul Sater, Paul E Clavijo, Nancy Judd, Edward Tsong, Chris Silvin, Patrick Soon-Shiong, Michelle R Padget, Jeffrey Schlom, James Hodge, Christian Hinrichs, Clint Allen

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e002128; DOI: 10.1136/jitc-2020-002128
Prediction of severe immune-related adverse events requiring hospital admission in patients on immune checkpoint inhibitors: study of a population level insurance claims database from the USA
Mark Kalinich, William Murphy, Shannon Wongvibulsin, Vartan Pahalyants, Kun-Hsing Yu, Chenyue Lu, Feicheng Wang, Leyre Zubiri, Vivek Naranbhai, Alexander Gusev, Shawn G Kwatra, Kerry L Reynolds, Yevgeniy R Semenov

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001935; DOI: 10.1136/jitc-2020-001935
Interrogation of the cellular immunome of cancer patients with regard to the COVID-19 pandemic
Renee N Donahue, Jennifer L Marté, Meghali Goswami, Nicole J Toney, Yo-Ting Tsai, James L Gulley, Jeffrey Schlom

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e002087; DOI: 10.1136/jitc-2020-002087
Regorafenib enhances antitumor immunity via inhibition of p38 kinase/Creb1/Klf4 axis in tumor-associated macrophages
Da-Liang Ou, Chia-Wei Chen, Chia-Lang Hsu, Chih-Hung Chung, Zi-Rui Feng, Bin-Shyun Lee, Ann-Lii Cheng, Muh-Hwa Yang, Chiun Hsu

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001657; DOI: 10.1136/jitc-2020-001657
Complete metabolic response in patients with advanced non-small cell lung cancer with prolonged response to immune checkpoint inhibitor therapy
Justin Ferdinandus, Martin Metzenmacher, Lukas Kessler, Lale Umutlu, Clemens Aigner, Karl-Otto Kambartel, Viktor Grünwald, Wilfried Ernst Erich Eberhardt, Wolfgang Peter Fendler, Ken Herrmann, Martin Faehling, Daniel Christian Christoph

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e002262; DOI: 10.1136/jitc-2020-002262
Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model
Tereza Andreou, Jennifer Williams, Rebecca J Brownlie, Robert J Salmond, Erica Watson, Gary Shaw, Alan Melcher, Heiko Wurdak, Susan C Short, Mihaela Lorger

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001143; DOI: 10.1136/jitc-2020-001143
Effect of cabazitaxel on macrophages improves CD47-targeted immunotherapy for triple-negative breast cancer
Xu Cao, Bolei Li, Jing Chen, Jessica Dang, Siqi Chen, E Gulsen Gunes, Bo Xu, Lei Tian, Sabina Muend, Mustafa Raoof, Christiane Querfeld, Jianhua Yu, Steven T. Rosen, Yingyu Wang, Mingye Feng

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e002022; DOI: 10.1136/jitc-2020-002022
Complement C3a and C5a receptor blockade modulates regulatory T cell conversion in head and neck cancer
Jacob Gadwa, Thomas E Bickett, Laurel B Darragh, Michael William Knitz, Shilpa Bhatia, Miles Piper, Benjamin Van Court, Shiv Bhuvane, Diemmy Nguyen, Varuna Nangia, Emily K Kleczko, Raphael A Nemenoff, Sana D Karam

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e002585; DOI: 10.1136/jitc-2021-002585
Tumor-derived ILT4 induces T cell senescence and suppresses tumor immunity
Aiqin Gao, Xia Liu, Wenli Lin, Jingnan Wang, Shuyun Wang, Fusheng Si, Lan Huang, Yangjing Zhao, Yuping Sun, Guangyong Peng

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001536; DOI: 10.1136/jitc-2020-001536

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