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  • Recombinant Mycobacterium smegmatis delivering a fusion protein of human macrophage migration inhibitory factor (MIF) and IL-7 exerts an anticancer effect by inducing an immune response against MIF in a tumor-bearing mouse model

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Oncolytic and local immunotherapy
Original research
Recombinant Mycobacterium smegmatis delivering a fusion protein of human macrophage migration inhibitory factor (MIF) and IL-7 exerts an anticancer effect by inducing an immune response against MIF in a tumor-bearing mouse model

Authors

  • Hyein Jeong Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul 110799, KoreaDepartment of Biomedical Sciences, College of Medicine, Seoul National Universtiy, Seoul 03080, KoreaLiver Research Institute, College of Medicine, Seoul National University, Seoul 03080, KoreaCancer Research Institute, College of Medicine, Seoul National University, Seoul 03080, KoreaSeoul National University Medical Research Center (SNUMRC), Seoul 03080, Korea PubMed articlesGoogle scholar articles
  • So-Young Lee Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul 110799, KoreaLiver Research Institute, College of Medicine, Seoul National University, Seoul 03080, KoreaCancer Research Institute, College of Medicine, Seoul National University, Seoul 03080, KoreaSeoul National University Medical Research Center (SNUMRC), Seoul 03080, Korea PubMed articlesGoogle scholar articles
  • Hyejun Seo Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul 110799, KoreaLiver Research Institute, College of Medicine, Seoul National University, Seoul 03080, KoreaCancer Research Institute, College of Medicine, Seoul National University, Seoul 03080, KoreaSeoul National University Medical Research Center (SNUMRC), Seoul 03080, Korea PubMed articlesGoogle scholar articles
  • Bum-Joon Kim Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul 110799, KoreaDepartment of Biomedical Sciences, College of Medicine, Seoul National Universtiy, Seoul 03080, KoreaLiver Research Institute, College of Medicine, Seoul National University, Seoul 03080, KoreaCancer Research Institute, College of Medicine, Seoul National University, Seoul 03080, KoreaSeoul National University Medical Research Center (SNUMRC), Seoul 03080, Korea PubMed articlesGoogle scholar articles

Citation

Jeong H, Lee S, Seo H, et al
Recombinant Mycobacterium smegmatis delivering a fusion protein of human macrophage migration inhibitory factor (MIF) and IL-7 exerts an anticancer effect by inducing an immune response against MIF in a tumor-bearing mouse model
Journal for ImmunoTherapy of Cancer 2021;9:e003180. doi: 10.1136/jitc-2021-003180
Online issue publication 
November 02, 2022

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.