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Immune cell therapies and immune cell engineering
Original research
VEGFR-2 redirected CAR-T cells are functionally impaired by soluble VEGF-A competition for receptor binding

Authors

  • Evripidis Lanitis Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles
  • Paris Kosti Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles
  • Catherine Ronet Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles
  • Elisabetta Cribioli Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles
  • Giorgia Rota Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles
  • Aodrenn Spill Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles
  • Patrick Reichenbach Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles
  • Vincent Zoete Computer-aided Molecular Engineering Group, Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles
  • Denarda Dangaj Laniti Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles
  • George Coukos Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles
  • Melita Irving Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Vaud, Switzerland PubMed articlesGoogle scholar articles

Citation

Lanitis E, Kosti P, Ronet C, et al
VEGFR-2 redirected CAR-T cells are functionally impaired by soluble VEGF-A competition for receptor binding
Journal for ImmunoTherapy of Cancer 2021;9:e002151. doi: 10.1136/jitc-2020-002151
Online issue publication 
November 02, 2022

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Copyright information

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.