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Clinical/translational cancer immunotherapy
Original research
Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects

Authors

  • Ratna Veeramachaneni Department of Head and Neck Surgery, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articlesGoogle scholar articles
  • Wangjie Yu Bobby R. Alford Department of Otolaryngology- Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA PubMed articlesGoogle scholar articles
  • Jared M Newton Bobby R. Alford Department of Otolaryngology- Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USAInterdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX, USA PubMed articlesGoogle scholar articles
  • Jan O Kemnade Hematology/Oncology Section; Medical Care Line, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USAHematology/Oncology Section, Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA PubMed articlesGoogle scholar articles
  • Heath D Skinner Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Andrew G Sikora Department of Head and Neck Surgery, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articlesGoogle scholar articles
  • Vlad C Sandulache Bobby R. Alford Department of Otolaryngology- Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USAENT Section; Operative Care Line, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USACenter for Translational Research on Inflammatory Diseases (CTRID), Michael E. DeBakey Veterans Affairs Medical Center, 77030, Texas, USA PubMed articlesGoogle scholar articles

Citation

Veeramachaneni R, Yu W, Newton JM, et al
Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects
Journal for ImmunoTherapy of Cancer 2021;9:e002773. doi: 10.1136/jitc-2021-002773
Online issue publication 
November 02, 2022

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Copyright information

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.