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  • Tumor mutational burden assessment in non-small-cell lung cancer samples: results from the TMB2 harmonization project comparing three NGS panels

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Immunotherapy biomarkers
Original research
Tumor mutational burden assessment in non-small-cell lung cancer samples: results from the TMB2 harmonization project comparing three NGS panels

Authors

  • Javier Ramos-Paradas H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, SpainSpanish Center for Biomedical Research Network in Oncology (CIBERONC), Madrid, Spain PubMed articlesGoogle scholar articles
  • Susana Hernández-Prieto Pathology-Targeted Therapies Laboratory, HM Sanchinarro University Hospital, Madrid, Spain PubMed articlesGoogle scholar articles
  • David Lora Scientific Support Unit, Health Research Institute Hospital 12 de Octubre (imas12), Madrid, SpainSpanish Center for Biomedical Research Network in Epidemiology and Public Health (CIBERESP), Madrid, SpainFaculty of Statistical Sciences, Complutense University, Madrid, Spain PubMed articlesGoogle scholar articles
  • Elena Sanchez Pathology-Targeted Therapies Laboratory, HM Sanchinarro University Hospital, Madrid, Spain PubMed articlesGoogle scholar articles
  • Aranzazu Rosado H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, Spain PubMed articlesGoogle scholar articles
  • Tamara Caniego-Casas Pathology Department, Ramón y Cajal Hospital, IRYCIS, Madrid, Spain PubMed articlesGoogle scholar articles
  • Nuria Carrizo H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, Spain PubMed articlesGoogle scholar articles
  • Ana Belén Enguita Pathology Department, 12 de Octubre Hospital, Madrid, Spain PubMed articlesGoogle scholar articles
  • María Teresa Muñoz-Jimenez H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, Spain PubMed articlesGoogle scholar articles
  • Borja Rodriguez H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, Spain PubMed articlesGoogle scholar articles
  • Urbicio Perez-Gonzalez Medical Oncology Department, 12 de Octubre Hospital, Madrid, Spain PubMed articlesGoogle scholar articles
  • David Gómez-Sánchez H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, SpainSpanish Center for Biomedical Research Network in Oncology (CIBERONC), Madrid, Spain PubMed articlesGoogle scholar articles
  • Irene Ferrer H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, SpainSpanish Center for Biomedical Research Network in Oncology (CIBERONC), Madrid, Spain PubMed articlesGoogle scholar articles
  • Santiago Ponce Aix H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, SpainSpanish Center for Biomedical Research Network in Oncology (CIBERONC), Madrid, SpainMedical Oncology Department, 12 de Octubre Hospital, Madrid, Spain PubMed articlesGoogle scholar articles
  • Ángel Nuñez Buiza H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, Spain PubMed articlesGoogle scholar articles
  • Pilar Garrido Spanish Center for Biomedical Research Network in Oncology (CIBERONC), Madrid, SpainMedical Oncology Department, Ramón y Cajal Hospital, IRYCIS, Madrid, SpainFaculty of Medicine, Alcalá de Henares University, Madrid, Spain PubMed articlesGoogle scholar articles
  • José Palacios Spanish Center for Biomedical Research Network in Oncology (CIBERONC), Madrid, SpainPathology Department, Ramón y Cajal Hospital, IRYCIS, Madrid, SpainFaculty of Medicine, Alcalá de Henares University, Madrid, Spain PubMed articlesGoogle scholar articles
  • Fernando Lopez-Rios Spanish Center for Biomedical Research Network in Oncology (CIBERONC), Madrid, SpainPathology-Targeted Therapies Laboratory, HM Sanchinarro University Hospital, Madrid, Spain PubMed articlesGoogle scholar articles
  • Eva M Garrido-Martin H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, SpainSpanish Center for Biomedical Research Network in Oncology (CIBERONC), Madrid, Spain PubMed articlesGoogle scholar articles
  • Luis Paz-Ares H12O-CNIO Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12) / Spanish National Cancer Research Center (CNIO), Madrid, SpainSpanish Center for Biomedical Research Network in Oncology (CIBERONC), Madrid, SpainMedical Oncology Department, 12 de Octubre Hospital, Madrid, SpainFaculty of Medicine, Complutense University, Madrid, Spain PubMed articlesGoogle scholar articles

Citation

Ramos-Paradas J, Hernández-Prieto S, Lora D, et al
Tumor mutational burden assessment in non-small-cell lung cancer samples: results from the TMB2 harmonization project comparing three NGS panels
Journal for ImmunoTherapy of Cancer 2021;9:e001904. doi: 10.1136/jitc-2020-001904
Online issue publication 
February 07, 2022

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.