Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma

Georgia M Beasley; Smita K Nair; Norma E Farrow; Karenia Landa; Maria Angelica Selim; Carol Ann Wiggs; Sin-Ho Jung; Darell D Bigner; Andrea True Kelly; Matthias Gromeier; April KS Salama

doi:10.1136/jitc-2020-002203

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Oncolytic and local immunotherapy

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Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma

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Georgia M Beasley Department of Surgery, Duke University, Durham, North Carolina, USA Duke Cancer Institute, Duke University, Durham, NC, USA PubMed articles Google scholar articles
Smita K Nair Department of Surgery, Duke University, Durham, North Carolina, USA Duke Cancer Institute, Duke University, Durham, NC, USA Department of Pathology, Duke University, Durham, North Carolina, USA Department of Neurosurgery, Duke University, Durham, NC, USA PubMed articles Google scholar articles
Norma E Farrow Department of Surgery, Duke University, Durham, North Carolina, USA PubMed articles Google scholar articles
Karenia Landa Department of Surgery, Duke University, Durham, North Carolina, USA PubMed articles Google scholar articles
Maria Angelica Selim Department of Pathology, Duke University, Durham, North Carolina, USA PubMed articles Google scholar articles
Carol Ann Wiggs Duke Cancer Institute, Duke University, Durham, NC, USA PubMed articles Google scholar articles
Sin-Ho Jung Duke Cancer Institute, Duke University, Durham, NC, USA Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA PubMed articles Google scholar articles
Darell D Bigner Duke Cancer Institute, Duke University, Durham, NC, USA Department of Pathology, Duke University, Durham, North Carolina, USA Department of Neurosurgery, Duke University, Durham, NC, USA PubMed articles Google scholar articles
Andrea True Kelly Istari Oncology Inc, Morrisville, North Carolina, USA PubMed articles Google scholar articles
Matthias Gromeier Duke Cancer Institute, Duke University, Durham, NC, USA Department of Neurosurgery, Duke University, Durham, NC, USA Department of Molecular Genetics and Biology, Duke University, Durham, NC, USA Department of Medicine, Duke Univeristy, Durham, NC, USA PubMed articles Google scholar articles
April KS Salama Duke Cancer Institute, Duke University, Durham, NC, USA Department of Medicine, Duke Univeristy, Durham, NC, USA PubMed articles Google scholar articles

Citation

Beasley GM, Nair SK, Farrow NE, et al

Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma

Journal for ImmunoTherapy of Cancer 2021;9:e002203. doi: 10.1136/jitc-2020-002203

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May 06, 2021

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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