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  • Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model

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Clinical/translational cancer immunotherapy
Original research
Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model

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Lee YS, O'Brien LJ, Walpole CM, et al
Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model
Journal for ImmunoTherapy of Cancer 2021;9:e001963. doi: 10.1136/jitc-2020-001963