Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche

Louise M E Müller; Gemma Migneco; Gina B Scott; Jenny Down; Sancha King; Basem Askar; Victoria Jennings; Babatunde Oyajobi; Karen Scott; Emma West; Christy Ralph; Adel Samson; Elizabeth J Ilett; Munitta Muthana; Matt Coffey; Alan Melcher; Christopher Parrish; Gordon Cook; Michelle Lawson; Fiona Errington-Mais

doi:10.1136/jitc-2020-001803

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Oncolytic and local immunotherapy

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Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche

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Louise M E Müller Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Gemma Migneco Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Gina B Scott Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Jenny Down Sheffield Myeloma Research Team, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK PubMed articles Google scholar articles
Sancha King Sheffield Myeloma Research Team, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK PubMed articles Google scholar articles
Basem Askar Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Victoria Jennings Division of Radiotherapy and Imaging, Institute of Cancer Research, London, UK PubMed articles Google scholar articles
Babatunde Oyajobi Cancer Therapy and Research Center, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA PubMed articles Google scholar articles
Karen Scott Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Emma West Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Christy Ralph Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Adel Samson Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Elizabeth J Ilett Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Munitta Muthana Sheffield Myeloma Research Team, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK PubMed articles Google scholar articles
Matt Coffey Oncolytics Biotech Inc, Calgary, Alberta, Canada PubMed articles Google scholar articles
Alan Melcher Division of Radiotherapy and Imaging, Institute of Cancer Research, London, UK PubMed articles Google scholar articles
Christopher Parrish Department of Haematology, St James's University Hospital, Leeds, UK PubMed articles Google scholar articles
Gordon Cook Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Michelle Lawson Sheffield Myeloma Research Team, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK PubMed articles Google scholar articles
Fiona Errington-Mais Division of Haematology and Immunology, Leeds Institute of Medical Research, University of Leeds, Leeds, UK PubMed articles Google scholar articles

Citation

Müller LME, Migneco G, Scott GB, et al

Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche

Journal for ImmunoTherapy of Cancer 2021;9:e001803. doi: 10.1136/jitc-2020-001803

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February 10, 2022

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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