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  • MYC oncogene is associated with suppression of tumor immunity and targeting Myc induces tumor cell immunogenicity for therapeutic whole cell vaccination

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Clinical/translational cancer immunotherapy
Original research
MYC oncogene is associated with suppression of tumor immunity and targeting Myc induces tumor cell immunogenicity for therapeutic whole cell vaccination

Authors

  • Xiaofang Wu The Sheikh Zayed Institute for Pediatric Surgical Innovation, Childrens Hospital Medical Center, Washington, District of Columbia, USA PubMed articlesGoogle scholar articles
  • Marie Nelson The Sheikh Zayed Institute for Pediatric Surgical Innovation, Childrens Hospital Medical Center, Washington, District of Columbia, USA PubMed articlesGoogle scholar articles
  • Mousumi Basu The Sheikh Zayed Institute for Pediatric Surgical Innovation, Childrens Hospital Medical Center, Washington, District of Columbia, USA PubMed articlesGoogle scholar articles
  • Priya Srinivasan The Sheikh Zayed Institute for Pediatric Surgical Innovation, Childrens Hospital Medical Center, Washington, District of Columbia, USA PubMed articlesGoogle scholar articles
  • Christopher Lazarski Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC, USA PubMed articlesGoogle scholar articles
  • Peng Zhang Division of Immunotherapy, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Pan Zheng Division of Immunotherapy, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Anthony David Sandler The Sheikh Zayed Institute for Pediatric Surgical Innovation, Childrens Hospital Medical Center, Washington, District of Columbia, USAJoseph E. Robert Jr. Center for Surgical Care, Childrens National Hospital, Washington, District of Columbia, USA PubMed articlesGoogle scholar articles

Citation

Wu X, Nelson M, Basu M, et al
MYC oncogene is associated with suppression of tumor immunity and targeting Myc induces tumor cell immunogenicity for therapeutic whole cell vaccination
Journal for ImmunoTherapy of Cancer 2021;9:e001388. doi: 10.1136/jitc-2020-001388
Online issue publication 
February 10, 2022

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.