Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy

Nina M. Muñoz; Malea Williams; Katherine Dixon; Crystal Dupuis; Amanda McWatters; Rony Avritscher; Soraya Zorro Manrique; Kevin McHugh; Ravi Murthy; Alda Tam; Aung Naing; Sapna P. Patel; David Leach; Jeffrey D. Hartgerink; Simon Young; Punit Prakash; Patrick Hwu; Rahul A. Sheth

doi:10.1136/jitc-2020-001800

Article info

PDF

PDF +
Supplementary
Material

XML

Oncolytic and local immunotherapy

Original research

Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy

Authors

Nina M. Muñoz Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Malea Williams Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Katherine Dixon Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Crystal Dupuis Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Amanda McWatters Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Rony Avritscher Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Soraya Zorro Manrique Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Kevin McHugh Department of Bioengineering, Rice University, Houston, Texas, USA PubMed articles Google scholar articles
Ravi Murthy Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USADepartment of Investigational Cancer Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Alda Tam Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Aung Naing Department of Investigational Cancer Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Sapna P. Patel Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
David Leach Department of Chemistry, Rice University, Houston, Texas, USA PubMed articles Google scholar articles
Jeffrey D. Hartgerink Department of Chemistry, Rice University, Houston, Texas, USA PubMed articles Google scholar articles
Simon Young Department of Oral and Maxillofacial Surgery, The University of Texas Health Science Center at Houston, Houston, Texas, USA PubMed articles Google scholar articles
Punit Prakash Department of Electrical and Computer Engineering, Kansas State University, Manhattan, Kansas, USA PubMed articles Google scholar articles
Patrick Hwu Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Rahul A. Sheth Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles

Citation

Muñoz NM, Williams M, Dixon K, et al

Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy

Journal for ImmunoTherapy of Cancer 2021;9:e001800. doi: 10.1136/jitc-2020-001800

Online issue publication

January 26, 2023

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Copyright information

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

Log in using your username and password

Main menu

Log in using your username and password

You are here

Authors

Citation

Request permissions

Copyright information

Read the full text or download the PDF:

Log in using your username and password