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  • Synergy between Toxoplasma gondii type I ΔGRA17 immunotherapy and PD-L1 checkpoint inhibition triggers the regression of targeted and distal tumors

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Oncolytic and local immunotherapy
Original research
Synergy between Toxoplasma gondii type I ΔGRA17 immunotherapy and PD-L1 checkpoint inhibition triggers the regression of targeted and distal tumors

Authors

  • Yu-Chao Zhu Department of Radiology, The Affiliated Hospital of Medical School of Ningbo University, Ningbo, Zhejiang, China Immunology Innovation Team, Ningbo University School of Medicine, Ningbo, Zhejiang, China PubMed articlesGoogle scholar articles
  • Hany M Elsheikha Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Loughborough, UK PubMed articlesGoogle scholar articles
  • Jian-Hua Wang Department of Radiology, The Affiliated Hospital of Medical School of Ningbo University, Ningbo, Zhejiang, China Immunology Innovation Team, Ningbo University School of Medicine, Ningbo, Zhejiang, China PubMed articlesGoogle scholar articles
  • Shuai Fang Department of Radiology, The Affiliated Hospital of Medical School of Ningbo University, Ningbo, Zhejiang, China Immunology Innovation Team, Ningbo University School of Medicine, Ningbo, Zhejiang, China PubMed articlesGoogle scholar articles
  • Jun-Jun He State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China PubMed articlesGoogle scholar articles
  • Xing-Quan Zhu College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, China Key Laboratory of Veterinary Public Health of Higher Education of Yunnan Province, College of Veterinary Medicine, Yunnan Agricultural University, Kunming, Yunnan, China PubMed articlesGoogle scholar articles
  • Jia Chen Department of Radiology, The Affiliated Hospital of Medical School of Ningbo University, Ningbo, Zhejiang, China Immunology Innovation Team, Ningbo University School of Medicine, Ningbo, Zhejiang, China PubMed articlesGoogle scholar articles

Citation

Zhu Y, Elsheikha HM, Wang J, et al
Synergy between Toxoplasma gondii type I ΔGRA17 immunotherapy and PD-L1 checkpoint inhibition triggers the regression of targeted and distal tumors
Journal for ImmunoTherapy of Cancer 2021;9:e002970. doi: 10.1136/jitc-2021-002970
Online issue publication 
May 08, 2023

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.