Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer

Shaoming Zhu; A-Hong Ma; Zheng Zhu; Elio Adib; Ting Rao; Na Li; Kaiyuan Ni; Veera Chandra Sekhar Reddy Chittepu; Rao Prabhala; Juan Garisto Risco; David Kwiatkowski; Kent Mouw; Guru Sonpavde; Fan Cheng; Chong-xian Pan

doi:10.1136/jitc-2021-002917

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Clinical/translational cancer immunotherapy

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Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer

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Shaoming Zhu Department of Internal Medicine, University of California Davis, Sacramento, CA, USADepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China PubMed articles Google scholar articles
A-Hong Ma Department of Biochemistry and Molecular Medicine, University of California Davis, Sacramento, CA, USA PubMed articles Google scholar articles
Zheng Zhu Department of Medicine, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Elio Adib Department of Medicine, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Ting Rao Department of Internal Medicine, University of California Davis, Sacramento, CA, USADepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China PubMed articles Google scholar articles
Na Li Department of Internal Medicine, University of California Davis, Sacramento, CA, USADepartment of Oncology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China PubMed articles Google scholar articles
Kaiyuan Ni Department of Bioengienering, Massachusetts Institute of Technology, Cambridge, MA, USA PubMed articles Google scholar articles
Veera Chandra Sekhar Reddy Chittepu Department of Medicine, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Rao Prabhala Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Juan Garisto Risco Department of Urology, VA Boston Healthcare System, Boston, MA, USA PubMed articles Google scholar articles
David Kwiatkowski Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Kent Mouw Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Guru Sonpavde Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Fan Cheng Department of Urology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China PubMed articles Google scholar articles
Chong-xian Pan Department of Internal Medicine, University of California Davis, Sacramento, CA, USADepartment of Medicine, Harvard Medical School, Boston, MA, USADepartment of Medicine, VA Boston Healthcare System, Boston, MA, USA PubMed articles Google scholar articles

Citation

Zhu S, Ma A, Zhu Z, et al

Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer

Journal for ImmunoTherapy of Cancer 2021;9:e002917. doi: 10.1136/jitc-2021-002917

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May 08, 2023

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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