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  • In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis

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Clinical/translational cancer immunotherapy
Original research
In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis

Authors

  • Seohyun Kim KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South KoreaCenter for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea PubMed articlesGoogle scholar articles
  • Seong A Kim Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea PubMed articlesGoogle scholar articles
  • Gi-Hoon Nam Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea PubMed articlesGoogle scholar articles
  • Yeonsun Hong Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea PubMed articlesGoogle scholar articles
  • Gi Beom Kim KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South KoreaCenter for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea PubMed articlesGoogle scholar articles
  • Yoonjeong Choi KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South KoreaCenter for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea PubMed articlesGoogle scholar articles
  • Seokyoung Lee Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea PubMed articlesGoogle scholar articles
  • Yuri Cho KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South KoreaCenter for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea PubMed articlesGoogle scholar articles
  • Minsu Kwon Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Korea University Hospital, Seoul, South Korea PubMed articlesGoogle scholar articles
  • Cherlhyun Jeong Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South KoreaKHU-KIST Department of Converging Science and Technology, Kyunghee University, Seoul, South Korea PubMed articlesGoogle scholar articles
  • Sehoon Kim KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South KoreaCenter for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea PubMed articlesGoogle scholar articles
  • In-San Kim KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South KoreaCenter for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea PubMed articlesGoogle scholar articles

Citation

Kim S, Kim SA, Nam G, et al
In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis
Journal for ImmunoTherapy of Cancer 2021;9:e001481. doi: 10.1136/jitc-2020-001481
Online issue publication 
November 23, 2023

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.