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  • p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy

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Clinical/translational cancer immunotherapy
Original research
p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy

Authors

  • Chunwan Lu Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, United States Charlie Norwood VA Medical Center, Augusta, Georgia, United States PubMed articlesGoogle scholar articles
  • John D Klement Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, United States Charlie Norwood VA Medical Center, Augusta, Georgia, United States PubMed articlesGoogle scholar articles
  • Alyssa D Smith Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, United States Charlie Norwood VA Medical Center, Augusta, Georgia, United States PubMed articlesGoogle scholar articles
  • Dafeng Yang Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, United States Charlie Norwood VA Medical Center, Augusta, Georgia, United States PubMed articlesGoogle scholar articles
  • Jennifer L Waller Department of Population Health Sciences, Augusta University, Augusta, Georgia, United States PubMed articlesGoogle scholar articles
  • Darren D Browning Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, United States PubMed articlesGoogle scholar articles
  • David H Munn Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, United States PubMed articlesGoogle scholar articles
  • Kebin Liu Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, United States Charlie Norwood VA Medical Center, Augusta, Georgia, United States PubMed articlesGoogle scholar articles

Citation

Lu C, Klement JD, Smith AD, et al
p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy
Journal for ImmunoTherapy of Cancer 2020;8:e001365. doi: 10.1136/jitc-2020-001365
Online issue publication 
October 13, 2020

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.