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  • Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects

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Clinical/translational cancer immunotherapy
Original research
Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects

Authors

  • Julia Delahousse Molecular Radiotherapy and Innovative Therapeutics, Unité Mixte de Recherche 1030 INSERM, Gustave Roussy, F-94805, Villejuif, France Vectorology and Anticancer Therapies, Unité Mixte de Recherche 8203 Centre National de la Recherche Scientifique, Gustave Roussy, F-94805, Villejuif, France PubMed articlesGoogle scholar articles
  • Charles Skarbek Vectorology and Anticancer Therapies, Unité Mixte de Recherche 8203 Centre National de la Recherche Scientifique, Gustave Roussy, F-94805, Villejuif, France PubMed articlesGoogle scholar articles
  • Mélanie Desbois Laboratoire d'immunomonitoring En Oncologie, Gustave Roussy, F-94805, Villejuif, France PubMed articlesGoogle scholar articles
  • Jean-Luc Perfettini Molecular Radiotherapy and Innovative Therapeutics, Unité Mixte de Recherche 1030 INSERM, Gustave Roussy, F-94805, Villejuif, France PubMed articlesGoogle scholar articles
  • Nathalie Chaput Laboratoire d'immunomonitoring En Oncologie, Gustave Roussy, F-94805, Villejuif, France Laboratory of Genetic Instability and Oncogenesis, Unité Mixte de Recherche 8200 Centre National de la Recherche Scientifique, Gustave Roussy Institute, F-94805, Villejuif, France Faculté de Pharmacie, Université Paris-Saclay, F-92296, Chatenay-Malabry, France PubMed articlesGoogle scholar articles
  • Angelo Paci Molecular Radiotherapy and Innovative Therapeutics, Unité Mixte de Recherche 1030 INSERM, Gustave Roussy, F-94805, Villejuif, France Faculté de Pharmacie, Université Paris-Saclay, F-92296, Chatenay-Malabry, France Pharmacology Department, Gustave Roussy, Villejuif, France PubMed articlesGoogle scholar articles

Citation

Delahousse J, Skarbek C, Desbois M, et al
Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects
Journal for ImmunoTherapy of Cancer 2020;8:e000916. doi: 10.1136/jitc-2020-000916
Online issue publication 
August 11, 2020

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.