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Basic tumor immunology
Original research
Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer

Authors

  • Kenji Fujiwara Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States JSPS Overseas Research Fellow, Japan Society for the Promotion of Science, Tokyo, Japan PubMed articlesGoogle scholar articles
  • May Tun Saung Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles
  • Hao Jing Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles
  • Brian Herbst Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States Graduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles
  • MacKenzie Zarecki Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles
  • Stephen Muth Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles
  • Annie Wu Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles
  • Elaine Bigelow Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles
  • Linda Chen Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Hepato-Bilio-Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China PubMed articlesGoogle scholar articles
  • Keyu Li Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Hepato-Bilio-Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China PubMed articlesGoogle scholar articles
  • Neolle Jurcak Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States Graduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles
  • Alex B Blair Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles
  • Ding Ding Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles
  • Michael Wichroski Bristol Myers Squibb Co, Princeton, New Jersey, USA PubMed articlesGoogle scholar articles
  • Jordan Blum Bristol Myers Squibb Co, Princeton, New Jersey, USA PubMed articlesGoogle scholar articles
  • Nathan Cheadle Bristol Myers Squibb Co, Princeton, New Jersey, USA PubMed articlesGoogle scholar articles
  • Jennifer Koenitzer Bristol Myers Squibb Co, Princeton, New Jersey, USA PubMed articlesGoogle scholar articles
  • Lei Zheng Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States Pancreatic Cancer Precision Medicine Center of Excellence Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States Graduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States PubMed articlesGoogle scholar articles

Citation

Fujiwara K, Saung MT, Jing H, et al
Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer
Journal for ImmunoTherapy of Cancer 2020;8:e000351. doi: 10.1136/jitc-2019-000351
Online issue publication 
July 16, 2020

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.