PRKDC: new biomarker and drug target for checkpoint blockade immunotherapy

Kien Thiam Tan; Chun-Nan Yeh; Yu-Chan Chang; Jen-Hao Cheng; Wen-Liang Fang; Yi-Chen Yeh; Yu-Chao Wang; Dennis Shin-Shian Hsu; Chiao-En Wu; Jiun-I Lai; Peter Mu-Hsin Chang; Ming-Han Chen; Meng-Lun Lu; Shu-Jen Chen; Yee Chao; Michael Hsiao; Ming-Huang Chen

doi:10.1136/jitc-2019-000485

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Immunotherapy biomarkers

Original research

PRKDC: new biomarker and drug target for checkpoint blockade immunotherapy

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Kien Thiam Tan ACT Genomics Co., Ltd, Taipei, Taiwan PubMed articles Google scholar articles
Chun-Nan Yeh Department of Surgery, Liver Research Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan PubMed articles Google scholar articles
Yu-Chan Chang Genomics Research Center, Academia Sinica, Taipei, Taiwan PubMed articles Google scholar articles
Jen-Hao Cheng ACT Genomics Co., Ltd, Taipei, Taiwan PubMed articles Google scholar articles
Wen-Liang Fang Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan School of Medicine, National Yang-Ming University, Taipei, Taiwan PubMed articles Google scholar articles
Yi-Chen Yeh School of Medicine, National Yang-Ming University, Taipei, Taiwan Department of Pathology, Taipei Veterans General Hospital, Taipei, Taiwan PubMed articles Google scholar articles
Yu-Chao Wang Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan Preventive Medicine Research Center, National Yang-Ming University, Taipei, Taiwan PubMed articles Google scholar articles
Dennis Shin-Shian Hsu Asclepiumm Taiwan Co., Ltd, New Taipei, Taiwan PubMed articles Google scholar articles
Chiao-En Wu Department of Surgery, Liver Research Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan PubMed articles Google scholar articles
Jiun-I Lai School of Medicine, National Yang-Ming University, Taipei, Taiwan Center of Immuno-Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan PubMed articles Google scholar articles
Peter Mu-Hsin Chang School of Medicine, National Yang-Ming University, Taipei, Taiwan Center of Immuno-Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan PubMed articles Google scholar articles
Ming-Han Chen School of Medicine, National Yang-Ming University, Taipei, Taiwan PubMed articles Google scholar articles
Meng-Lun Lu Center of Immuno-Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan PubMed articles Google scholar articles
Shu-Jen Chen ACT Genomics Co., Ltd, Taipei, Taiwan PubMed articles Google scholar articles
Yee Chao School of Medicine, National Yang-Ming University, Taipei, Taiwan Center of Immuno-Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan PubMed articles Google scholar articles
Michael Hsiao Genomics Research Center, Academia Sinica, Taipei, Taiwan PubMed articles Google scholar articles
Ming-Huang Chen School of Medicine, National Yang-Ming University, Taipei, Taiwan Center of Immuno-Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan PubMed articles Google scholar articles

Citation

Tan KT, Yeh C, Chang Y, et al

PRKDC: new biomarker and drug target for checkpoint blockade immunotherapy

Journal for ImmunoTherapy of Cancer 2020;8:e000485. doi: 10.1136/jitc-2019-000485

Online issue publication

January 11, 2022

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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