CCR5 blockade inflames antitumor immunity in BAP1-mutant clear cell renal cell carcinoma

Quan Zhou; Yangyang Qi; Zewei Wang; Han Zeng; Hongyu Zhang; Zhaopei Liu; Qiuren Huang; Ying Xiong; Jiajun Wang; Yuan Chang; Qi Bai; Yu Xia; Yiwei Wang; Li Liu; Le Xu; Bo Dai; Jianming Guo; Yu Zhu; Weijuan Zhang; Jiejie Xu

doi:10.1136/jitc-2019-000228

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Clinical/translational cancer immunotherapy

Original research

CCR5 blockade inflames antitumor immunity in BAP1-mutant clear cell renal cell carcinoma

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Quan Zhou Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China PubMed articles Google scholar articles
Yangyang Qi Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China PubMed articles Google scholar articles
Zewei Wang Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China PubMed articles Google scholar articles
Han Zeng Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China PubMed articles Google scholar articles
Hongyu Zhang Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China PubMed articles Google scholar articles
Zhaopei Liu Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China PubMed articles Google scholar articles
Qiuren Huang Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China PubMed articles Google scholar articles
Ying Xiong Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China PubMed articles Google scholar articles
Jiajun Wang Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China PubMed articles Google scholar articles
Yuan Chang Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China PubMed articles Google scholar articles
Qi Bai Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China PubMed articles Google scholar articles
Yu Xia Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China PubMed articles Google scholar articles
Yiwei Wang Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China PubMed articles Google scholar articles
Li Liu Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China PubMed articles Google scholar articles
Le Xu Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China PubMed articles Google scholar articles
Bo Dai Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China PubMed articles Google scholar articles
Jianming Guo Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China PubMed articles Google scholar articles
Yu Zhu Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China PubMed articles Google scholar articles
Weijuan Zhang Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China PubMed articles Google scholar articles
Jiejie Xu Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China PubMed articles Google scholar articles

Citation

Zhou Q, Qi Y, Wang Z, et al

CCR5 blockade inflames antitumor immunity in BAP1-mutant clear cell renal cell carcinoma

Journal for ImmunoTherapy of Cancer 2020;8:e000228. doi: 10.1136/jitc-2019-000228

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January 11, 2022

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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