Non-thermal histotripsy tumor ablation promotes abscopal immune responses that enhance cancer immunotherapy

Shibin Qu; Tejaswi Worlikar; Amy E Felsted; Anutosh Ganguly; Megan V Beems; Ryan Hubbard; Ashley L Pepple; Alicia A Kevelin; Hannah Garavaglia; Joe Dib; Mariam Toma; Hai Huang; Allan Tsung; Zhen Xu; Clifford Suhyun Cho

doi:10.1136/jitc-2019-000200

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Clinical/translational cancer immunotherapy

Original research

Non-thermal histotripsy tumor ablation promotes abscopal immune responses that enhance cancer immunotherapy

Authors

Shibin Qu Surgery, University of Michigan, Ann Arbor, Michigan, USA Department of Hepatobiliary Surgery, Xijing Hospital, Xian, Shaanxi, China PubMed articles Google scholar articles
Tejaswi Worlikar Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Amy E Felsted Surgery, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Anutosh Ganguly Surgery, University of Michigan, Ann Arbor, Michigan, USA Surgery, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Megan V Beems Surgery, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Ryan Hubbard Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Ashley L Pepple Surgery, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Alicia A Kevelin Surgery, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Hannah Garavaglia Surgery, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Joe Dib Surgery, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Mariam Toma Surgery, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Hai Huang Surgery, Ohio State University Medical Center, Columbus, Ohio, USA PubMed articles Google scholar articles
Allan Tsung Surgery, Ohio State University Medical Center, Columbus, Ohio, USA PubMed articles Google scholar articles
Zhen Xu Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA PubMed articles Google scholar articles
Clifford Suhyun Cho Surgery, University of Michigan, Ann Arbor, Michigan, USA Surgery, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA PubMed articles Google scholar articles

Citation

Qu S, Worlikar T, Felsted AE, et al

Non-thermal histotripsy tumor ablation promotes abscopal immune responses that enhance cancer immunotherapy

Journal for ImmunoTherapy of Cancer 2020;8:e000200. doi: 10.1136/jitc-2019-000200

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January 11, 2022

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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