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Research Article
Tumor microenvironment-derived S100A8/A9 is a novel prognostic biomarker for advanced melanoma patients and during immunotherapy with anti-PD-1 antibodies

Authors

  • Nikolaus B. Wagner Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany Department of DermatologyUniversity Hospital Tuebingen Tuebingen Germany Department of Dermatology, Venereology and AllergologyCantonal Hospital St. Gallen Rorschacher Strasse 95 9007 St. Gallen Switzerland PubMed articlesGoogle scholar articles
  • Benjamin Weide Department of DermatologyUniversity Hospital Tuebingen Tuebingen Germany PubMed articlesGoogle scholar articles
  • Mirko Gries Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany PubMed articlesGoogle scholar articles
  • Maike Reith Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany PubMed articlesGoogle scholar articles
  • Kathrin Tarnanidis Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany PubMed articlesGoogle scholar articles
  • Valerie Schuermans Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany PubMed articlesGoogle scholar articles
  • Charlotte Kemper Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany PubMed articlesGoogle scholar articles
  • Coretta Kehrel Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany PubMed articlesGoogle scholar articles
  • Anne Funder Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany PubMed articlesGoogle scholar articles
  • Ramtin Lichtenberger Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany PubMed articlesGoogle scholar articles
  • Antje Sucker Department of DermatologyUniversity Hospital Essen Essen Germany PubMed articlesGoogle scholar articles
  • Esther Herpel NCT Tissue Bank, National Center of Tumor Diseases (NCT) Heidelberg Germany Institute of PathologyUniversity Hospital Heidelberg Heidelberg Germany PubMed articlesGoogle scholar articles
  • Tim Holland-Letz Division of BiostatisticsGerman Cancer Research Center (DKFZ) Heidelberg Germany PubMed articlesGoogle scholar articles
  • Dirk Schadendorf Department of DermatologyUniversity Hospital Essen Essen Germany PubMed articlesGoogle scholar articles
  • Claus Garbe Department of DermatologyUniversity Hospital Tuebingen Tuebingen Germany PubMed articlesGoogle scholar articles
  • Viktor Umansky Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany PubMed articlesGoogle scholar articles
  • Jochen Utikal Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany PubMed articlesGoogle scholar articles
  • Christoffer Gebhardt Skin Cancer Unit, German Cancer Research Center (DKFZ) Heidelberg Germany Department of Dermatology, Venereology and AllergologyUniversity Medical Center Mannheim, Ruprecht-Karl University of Heidelberg Mannheim Germany Skin Cancer Center, Department of Dermatology and VenereologyUniversity Hospital Hamburg-Eppendorf (UKE) Hamburg Germany PubMed articlesGoogle scholar articles

Citation

Wagner NB, Weide B, Gries M, et al
Tumor microenvironment-derived S100A8/A9 is a novel prognostic biomarker for advanced melanoma patients and during immunotherapy with anti-PD-1 antibodies
Journal for ImmunoTherapy of Cancer 2019;7:343. doi: 10.1186/s40425-019-0828-1
Online issue publication 
January 08, 2022

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© The Author(s). Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.