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Research Article
Tumor-released autophagosomes induces CD4+ T cell-mediated immunosuppression via a TLR2–IL-6 cascade

Authors

  • Yong-Qiang Chen Department of Microbiology and ImmunologyMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China PubMed articlesGoogle scholar articles
  • Peng-Cheng Li Department of Microbiology and ImmunologyMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China PubMed articlesGoogle scholar articles
  • Ning Pan Department of Microbiology and ImmunologyMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China PubMed articlesGoogle scholar articles
  • Rong Gao Department of Microbiology and ImmunologyMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China PubMed articlesGoogle scholar articles
  • Zhi-Fa Wen Department of Microbiology and ImmunologyMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China PubMed articlesGoogle scholar articles
  • Tian-Yu Zhang Department of Microbiology and ImmunologyMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China PubMed articlesGoogle scholar articles
  • Fang Huang Department of Microbiology and ImmunologyMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China PubMed articlesGoogle scholar articles
  • Fang-Yuan Wu Department of Obstetrics and Gynecology, Zhongda HospitalMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China PubMed articlesGoogle scholar articles
  • Xi-Long Ou Department of Gastroenterology, Zhongda HospitalMedical School of Southeast University 210009 Nanjing China PubMed articlesGoogle scholar articles
  • Jin-Ping Zhang Institutes of Biology and Medical SciencesSoochow University 215123 Suzhou China PubMed articlesGoogle scholar articles
  • Xue-Jun Zhu Department of Microbiology and ImmunologyMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China Jiangsu Province Hospital of Traditional Chinese MedicineThe Affiliated Hospital of Nanjing University of Chinese Medicine 210029 Nanjing China PubMed articlesGoogle scholar articles
  • Hong-Ming Hu Department of Microbiology and ImmunologyMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China Robert W. Franz Cancer Research Center, Earle A. Chiles Research InstituteProvidence Portland Medical Center 97213 Portland OR USA PubMed articlesGoogle scholar articles
  • Kang Chen Department of Obstetrics and Gynecology and Barbara Ann Karmanos Cancer Institute, Wayne State University, Mucosal Immunology Studies TeamNational Institute of Allergy and Infectious Diseases, National Institutes of Health 48201 Detroit MI USA Jiangsu Province Hospital of Traditional Chinese MedicineThe Affiliated Hospital of Nanjing University of Chinese Medicine 210029 Nanjing China PubMed articlesGoogle scholar articles
  • Yun-Lang Cai Department of Obstetrics and Gynecology, Zhongda HospitalMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China PubMed articlesGoogle scholar articles
  • Li-Xin Wang Department of Microbiology and ImmunologyMedical School of Southeast University 87 Dingjiaqiao Road 210009 Nanjing China PubMed articlesGoogle scholar articles

Citation

Chen Y, Li P, Pan N, et al
Tumor-released autophagosomes induces CD4+ T cell-mediated immunosuppression via a TLR2–IL-6 cascade
Journal for ImmunoTherapy of Cancer 2019;7:178. doi: 10.1186/s40425-019-0646-5
Online issue publication 
January 08, 2022

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© The Author(s). Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.