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Tumor genomic alterations in severe-combined immunodeficiency bare-lymphocyte syndrome genes are associated with high mutational burden and disproportional neo-antigen rates

Authors

  • Yu Wang Department of BiostatisticsVanderbilt University Medical Center 37232 Nashville TN USA Center for Quantitative SciencesVanderbilt University Medical Center 2200 Pierce Ave, 777 PRB 37232–6307 Nashville TN USA PubMed articlesGoogle scholar articles
  • Douglas B. Johnson Division of Hematology and Oncology, Department of MedicineVanderbilt University Medical Center 37232 Nashville TN USA PubMed articlesGoogle scholar articles
  • Steve Lu Johns Hopkins University School of Medicine 21287 Baltimore MD USA PubMed articlesGoogle scholar articles
  • Luis A. Diaz Memorial Sloan Kettering Cancer Center 10065 New York NY USA PubMed articlesGoogle scholar articles
  • Yaomin Xu Department of BiostatisticsVanderbilt University Medical Center 37232 Nashville TN USA Center for Quantitative SciencesVanderbilt University Medical Center 2200 Pierce Ave, 777 PRB 37232–6307 Nashville TN USA PubMed articlesGoogle scholar articles
  • Justin M. Balko Division of Hematology and Oncology, Department of MedicineVanderbilt University Medical Center 37232 Nashville TN USA Breast Cancer Research ProgramVanderbilt University Medical Center 37232 Nashville TN USA PubMed articlesGoogle scholar articles

Citation

Wang Y, Johnson DB, Lu S, et al
Tumor genomic alterations in severe-combined immunodeficiency bare-lymphocyte syndrome genes are associated with high mutational burden and disproportional neo-antigen rates
Journal for ImmunoTherapy of Cancer 2019;7:123. doi: 10.1186/s40425-019-0584-2
Online issue publication 
January 08, 2022

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© The Author(s). Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.