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Research Article
A novel spontaneous hepatocellular carcinoma mouse model for studying T-cell exhaustion in the tumor microenvironment

Authors

  • Yu-Tzu Liu Institute of Molecular and Genomic Medicine, National Health Research Institutes No.35, Keyan Road 350 Zhunan Town Miaoli County Taiwan PubMed articlesGoogle scholar articles
  • Tai-Chung Tseng Division of Gastroenterology and Hepatology, Department of Internal MedicineNational Taiwan University Hospital Taipei Taiwan Hepatitis Research CenterNational Taiwan University, National Taiwan University Hospital Taipei Taiwan PubMed articlesGoogle scholar articles
  • Ruey-Shyang Soong Department of General SurgeryChang Gung Memorial Hospital Keelung Taiwan College of MedicineChang Gung University Taoyuan Taiwan PubMed articlesGoogle scholar articles
  • Chun-Yi Peng Institute of Molecular and Genomic Medicine, National Health Research Institutes No.35, Keyan Road 350 Zhunan Town Miaoli County Taiwan PubMed articlesGoogle scholar articles
  • Yu-Hsing Cheng Institute of Molecular and Genomic Medicine, National Health Research Institutes No.35, Keyan Road 350 Zhunan Town Miaoli County Taiwan PubMed articlesGoogle scholar articles
  • Shiu-Feng Huang Institute of Molecular and Genomic Medicine, National Health Research Institutes No.35, Keyan Road 350 Zhunan Town Miaoli County Taiwan PubMed articlesGoogle scholar articles
  • Tsung-Hsien Chuang Immunology Research CenterNational Health Research Institutes Miaoli Taiwan PubMed articlesGoogle scholar articles
  • Jia-Horng Kao Division of Gastroenterology and Hepatology, Department of Internal MedicineNational Taiwan University Hospital Taipei Taiwan Hepatitis Research CenterNational Taiwan University, National Taiwan University Hospital Taipei Taiwan Graduate Institute of Clinical MedicineNational Taiwan University Taipei Taiwan Department of Medical ResearchNational Taiwan University, National Taiwan University Hospital Taipei Taiwan PubMed articlesGoogle scholar articles
  • Li-Rung Huang Institute of Molecular and Genomic Medicine, National Health Research Institutes No.35, Keyan Road 350 Zhunan Town Miaoli County Taiwan Graduate Institute of Clinical MedicineNational Taiwan University Taipei Taiwan PubMed articlesGoogle scholar articles

Citation

Liu Y, Tseng T, Soong R, et al
A novel spontaneous hepatocellular carcinoma mouse model for studying T-cell exhaustion in the tumor microenvironment
Journal for ImmunoTherapy of Cancer 2018;6:144. doi: 10.1186/s40425-018-0462-3
Online issue publication 
February 09, 2021

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© The Author(s). Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.