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  • P04.04 Single cell transcriptomics reveals cancer associated fibroblasts enable modeling of tumor associated macrophage like phenotypes and treatment responses in primary colorectal cancer organoid cultures

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Poster Presentations
04. Precision medicine meets immunotherapy (immuno-monitoring)
P04.04 Single cell transcriptomics reveals cancer associated fibroblasts enable modeling of tumor associated macrophage like phenotypes and treatment responses in primary colorectal cancer organoid cultures

Authors

  • J Kabiljo Medical University of Vienna, Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Wien, Austria Ludwig Boltzmann Institute Applied Diagnostics, Medical University of Vienna, Vienna, Austria PubMed articlesGoogle scholar articles
  • A Theophil Medical University of Vienna, Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Vienna, Austria Ludwig Boltzmann Institute Applied Diagnostics, Medical University of Vienna, Vienna, Austria PubMed articlesGoogle scholar articles
  • J Homola Medical University of Vienna, Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Wien, Austria PubMed articlesGoogle scholar articles
  • A Renner Medical University of Vienna, Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Vienna, Austria PubMed articlesGoogle scholar articles
  • J Karall Medical University of Vienna, Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Vienna, Austria PubMed articlesGoogle scholar articles
  • N Hartman Medical University of Vienna, Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Vienna, Austria PubMed articlesGoogle scholar articles
  • S Stang Medical University of Vienna, Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Austria, Vienna, Austria PubMed articlesGoogle scholar articles
  • L Tran Ludwig Boltzmann Institute Applied Diagnostics, Medical University of Vienna, Vienna, Austria PubMed articlesGoogle scholar articles
  • J Laengle Medical University of Vienna, Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Vienna, Austria Ludwig Boltzmann Institute Applied Diagnostics, Medical University of Vienna, Vienna, Austria PubMed articlesGoogle scholar articles
  • A Kulu Medical University of Vienna, Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Vienna, Austria PubMed articlesGoogle scholar articles
  • A Chen Medical University of Vienna, Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Vienna, Austria PubMed articlesGoogle scholar articles
  • M Fabits Medical University of Vienna, Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Vienna, Austria PubMed articlesGoogle scholar articles
  • V Atanasova Medical University of Vienna, Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Austria, Vienna, Austria PubMed articlesGoogle scholar articles
  • H Walczak CECAD Cluster of Excellence, University of Cologne, Cologne, Germany Institute for Biochemistry I, Medical Faculty, University of Cologne, Cologne, Germany Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College, London, London, UK PubMed articlesGoogle scholar articles
  • D Herndler-Brandstetter Medical University of Vienna, Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Vienna, Austria PubMed articlesGoogle scholar articles
  • G Egger Ludwig Boltzmann Institute Applied Diagnostics, Medical University of Vienna, Vienna, Austria Medical University of Vienna, Department of Pathology, Comprehensive Cancer Center Vienna, Vienna, Austria PubMed articlesGoogle scholar articles
  • H Dolznig Medical University of Vienna, Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Vienna, Austria PubMed articlesGoogle scholar articles
  • A Kusienicka Medical University of Vienna, Department of Dermatology, Vienna, Austria PubMed articlesGoogle scholar articles
  • M Farlik Medical University of Vienna, Department of Dermatology, Vienna, Austria PubMed articlesGoogle scholar articles
  • M Bergmann Medical University of Vienna, Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Vienna, Austria Ludwig Boltzmann Institute Applied Diagnostics, Medical University of Vienna, Vienna, Austria PubMed articlesGoogle scholar articles

Citation

Kabiljo J, Theophil A, Homola J, et al
P04.04 Single cell transcriptomics reveals cancer associated fibroblasts enable modeling of tumor associated macrophage like phenotypes and treatment responses in primary colorectal cancer organoid cultures
Journal for ImmunoTherapy of Cancer 2024;12:doi: 10.1136/jitc-2024-ITOC10.39
Online issue publication 
March 20, 2024

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.