Nanoparticles targeting immune checkpoint protein VISTA induce potent antitumor immunity

Taylor J Moon; Hieu Minh Ta; Anubhuti Bhalotia; Kai E Paulsen; Diarmuid W Hutchinson; Gabrielle M Arkema; Andrew S Choi; Michiko G Haynie; Laolu Ogunnaike; Margee Dever; Li Lily Wang; Efstathios Karathanasis

doi:10.1136/jitc-2024-008977

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Oncolytic and local immunotherapy

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Nanoparticles targeting immune checkpoint protein VISTA induce potent antitumor immunity

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Taylor J Moon Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA PubMed articles Google scholar articles
Hieu Minh Ta Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, Ohio, USA PubMed articles Google scholar articles
Anubhuti Bhalotia Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA PubMed articles Google scholar articles
Kai E Paulsen Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA PubMed articles Google scholar articles
Diarmuid W Hutchinson Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA PubMed articles Google scholar articles
Gabrielle M Arkema Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA PubMed articles Google scholar articles
Andrew S Choi Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA PubMed articles Google scholar articles
Michiko G Haynie Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA PubMed articles Google scholar articles
Laolu Ogunnaike Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA PubMed articles Google scholar articles
Margee Dever Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA PubMed articles Google scholar articles
Li Lily Wang Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USADepartment of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, Ohio, USADepartment of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA PubMed articles Google scholar articles
Efstathios Karathanasis Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USACase Comprehensive Cancer Center, Cleveland, Ohio, USA PubMed articles Google scholar articles

Citation

Moon TJ, Ta HM, Bhalotia A, et al

Nanoparticles targeting immune checkpoint protein VISTA induce potent antitumor immunity

Journal for ImmunoTherapy of Cancer 2024;12:e008977. doi: 10.1136/jitc-2024-008977

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August 28, 2024

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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